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Dabigatran attenuates methotrexate-induced hepatotoxicity by regulating coagulation, endothelial dysfunction, and the NF-kB/IL-1β/MCP-1 and TLR4/NLRP3 signaling pathways.
El-Dessouki AM, Alzokaky AA, Raslan NA, Ibrahim S, Selim HMRM, Al-Karmalawy AA. El-Dessouki AM, et al. Among authors: al karmalawy aa. Naunyn Schmiedebergs Arch Pharmacol. 2024 Nov 11. doi: 10.1007/s00210-024-03567-w. Online ahead of print. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 39527308
Investigating the anti-inflammatory potential of N-amidic acid organoselenium candidates: biological assessments, molecular docking, and molecular dynamics simulations.
Althikrallah HA, Shaaban S, Elmaaty AA, Ba-Ghazal H, Almarri MN, Sharaky M, Alnajjar R, Al-Karmalawy AA. Althikrallah HA, et al. Among authors: al karmalawy aa. RSC Adv. 2024 Oct 9;14(44):31990-32000. doi: 10.1039/d4ra04762a. eCollection 2024 Oct 9. RSC Adv. 2024. PMID: 39391620 Free PMC article.
Muti-target rationale design of novel substituted N-phenyl-2-((6-phenylpyridazin-3-yl)thio)acetamide candidates as telomerase/JAK1/STAT3/TLR4 inhibitors: In vitro and in vivo investigations.
Shaldam MA, Mousa MHA, Tawfik HO, El-Dessouki AM, Sharaky M, Saleh MM, Alzahrani AYA, Moussa SB, Al-Karmalawy AA. Shaldam MA, et al. Among authors: al karmalawy aa. Bioorg Chem. 2024 Sep 24;153:107843. doi: 10.1016/j.bioorg.2024.107843. Online ahead of print. Bioorg Chem. 2024. PMID: 39332072
138 results