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Nuclear ATP-citrate lyase regulates chromatin-dependent activation and maintenance of the myofibroblast gene program.
Lazaropoulos MP, Gibb AA, Chapski DJ, Nair AA, Reiter AN, Roy R, Eaton DM, Bedi KC Jr, Margulies KB, Wellen KE, Estarás C, Vondriska TM, Elrod JW. Lazaropoulos MP, et al. Among authors: margulies kb. Nat Cardiovasc Res. 2024 Jul;3(7):869-882. doi: 10.1038/s44161-024-00502-3. Epub 2024 Jul 5. Nat Cardiovasc Res. 2024. PMID: 39196175 Free PMC article.
Mitochondrial protein hyperacetylation in the failing heart.
Horton JL, Martin OJ, Lai L, Riley NM, Richards AL, Vega RB, Leone TC, Pagliarini DJ, Muoio DM, Bedi KC Jr, Margulies KB, Coon JJ, Kelly DP. Horton JL, et al. Among authors: margulies kb. JCI Insight. 2016 Feb;2(1):e84897. doi: 10.1172/jci.insight.84897. Epub 2016 Feb 25. JCI Insight. 2016. PMID: 26998524 Free PMC article.
C-type natriuretic peptide co-ordinates cardiac structure and function.
Moyes AJ, Chu SM, Aubdool AA, Dukinfield MS, Margulies KB, Bedi KC, Hodivala-Dilke K, Baliga RS, Hobbs AJ. Moyes AJ, et al. Among authors: margulies kb. Eur Heart J. 2020 Mar 1;41(9):1006-1020. doi: 10.1093/eurheartj/ehz093. Eur Heart J. 2020. PMID: 30903134 Free PMC article.
Repurposing an anti-cancer agent for the treatment of hypertrophic heart disease.
Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J, Bedi KC Jr, Margulies KB, Sanz-Moreno V, Hobbs A, Hodivala-Dilke K. Dukinfield M, et al. Among authors: margulies kb. J Pathol. 2019 Dec;249(4):523-535. doi: 10.1002/path.5340. Epub 2019 Oct 30. J Pathol. 2019. PMID: 31424556 Free PMC article.
Cardiomyocyte d-dopachrome tautomerase protects against heart failure.
Ma Y, Su KN, Pfau D, Rao VS, Wu X, Hu X, Leng L, Du X, Piecychna M, Bedi K, Campbell SG, Eichmann A, Testani JM, Margulies KB, Bucala R, Young LH. Ma Y, et al. Among authors: margulies kb. JCI Insight. 2019 Sep 5;4(17):e128900. doi: 10.1172/jci.insight.128900. JCI Insight. 2019. PMID: 31484822 Free PMC article.
Targeting cardiac fibrosis with engineered T cells.
Aghajanian H, Kimura T, Rurik JG, Hancock AS, Leibowitz MS, Li L, Scholler J, Monslow J, Lo A, Han W, Wang T, Bedi K, Morley MP, Linares Saldana RA, Bolar NA, McDaid K, Assenmacher CA, Smith CL, Wirth D, June CH, Margulies KB, Jain R, Puré E, Albelda SM, Epstein JA. Aghajanian H, et al. Among authors: margulies kb. Nature. 2019 Sep;573(7774):430-433. doi: 10.1038/s41586-019-1546-z. Epub 2019 Sep 11. Nature. 2019. PMID: 31511695 Free PMC article.
297 results