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Human genomic DNA is widely interspersed with i-motif structures.
Peña Martinez CD, Zeraati M, Rouet R, Mazigi O, Henry JY, Gloss B, Kretzmann JA, Evans CW, Ruggiero E, Zanin I, Marušič M, Plavec J, Richter SN, Bryan TM, Smith NM, Dinger ME, Kummerfeld S, Christ D. Peña Martinez CD, et al. Among authors: christ d. EMBO J. 2024 Oct;43(20):4786-4804. doi: 10.1038/s44318-024-00210-5. Epub 2024 Aug 29. EMBO J. 2024. PMID: 39210146 Free PMC article.
I-motif DNA structures are formed in the nuclei of human cells.
Zeraati M, Langley DB, Schofield P, Moye AL, Rouet R, Hughes WE, Bryan TM, Dinger ME, Christ D. Zeraati M, et al. Among authors: christ d. Nat Chem. 2018 Jun;10(6):631-637. doi: 10.1038/s41557-018-0046-3. Epub 2018 Apr 23. Nat Chem. 2018. PMID: 29686376
DNA G-Quadruplex and i-Motif Structure Formation Is Interdependent in Human Cells.
King JJ, Irving KL, Evans CW, Chikhale RV, Becker R, Morris CJ, Peña Martinez CD, Schofield P, Christ D, Hurley LH, Waller ZAE, Iyer KS, Smith NM. King JJ, et al. Among authors: christ d. J Am Chem Soc. 2020 Dec 9;142(49):20600-20604. doi: 10.1021/jacs.0c11708. Epub 2020 Nov 30. J Am Chem Soc. 2020. PMID: 33253551
Bispecific antibodies with native chain structure.
Rouet R, Christ D. Rouet R, et al. Among authors: christ d. Nat Biotechnol. 2014 Feb;32(2):136-7. doi: 10.1038/nbt.2812. Nat Biotechnol. 2014. PMID: 24509759 No abstract available.
The retroelement Lx9 puts a brake on the immune response to virus infection.
Bartonicek N, Rouet R, Warren J, Loetsch C, Rodriguez GS, Walters S, Lin F, Zahra D, Blackburn J, Hammond JM, Reis ALM, Deveson IW, Zammit N, Zeraati M, Grey S, Christ D, Mattick JS, Chtanova T, Brink R, Dinger ME, Weatheritt RJ, Sprent J, King C. Bartonicek N, et al. Among authors: christ d. Nature. 2022 Aug;608(7924):757-765. doi: 10.1038/s41586-022-05054-9. Epub 2022 Aug 10. Nature. 2022. PMID: 35948641
193 results