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Screening Privileged Alkyl Guanidinium Motifs under Host-Mimicking Conditions Reveals a Novel Antibiotic with an Unconventional Mode of Action.
Schum D, Elsen FAV, Ruddell S, Schorpp K, Junca H, Müsken M, Chen SY, Fiedler MK, Pickl T, Pieper DH, Hadian K, Zacharias M, Sieber SA. Schum D, et al. Among authors: schorpp k. JACS Au. 2024 Jul 16;4(8):3125-3134. doi: 10.1021/jacsau.4c00449. eCollection 2024 Aug 26. JACS Au. 2024. PMID: 39211621 Free PMC article.
Farnesoid X receptor activation by bile acids suppresses lipid peroxidation and ferroptosis.
Tschuck J, Theilacker L, Rothenaigner I, Weiß SAI, Akdogan B, Lam VT, Müller C, Graf R, Brandner S, Pütz C, Rieder T, Schmitt-Kopplin P, Vincendeau M, Zischka H, Schorpp K, Hadian K. Tschuck J, et al. Among authors: schorpp k. Nat Commun. 2023 Oct 30;14(1):6908. doi: 10.1038/s41467-023-42702-8. Nat Commun. 2023. PMID: 37903763 Free PMC article.
Structure-based design, synthesis and evaluation of a novel family of PEX5-PEX14 interaction inhibitors against Trypanosoma.
Napolitano V, Mróz P, Marciniak M, Kalel VC, Softley CA, Janna Olmos JD, Tippler BG, Schorpp K, Rioton S, Fröhlich T, Plettenburg O, Hadian K, Erdmann R, Sattler M, Popowicz GM, Dawidowski M, Dubin G. Napolitano V, et al. Among authors: schorpp k. Eur J Med Chem. 2022 Dec 5;243:114778. doi: 10.1016/j.ejmech.2022.114778. Epub 2022 Sep 27. Eur J Med Chem. 2022. PMID: 36194937 Free article.
Author Correction: Retinoic acid signaling is critical during the totipotency window in early mammalian development.
Iturbide A, Ruiz Tejada Segura ML, Noll C, Schorpp K, Rothenaigner I, Ruiz-Morales ER, Lubatti G, Agami A, Hadian K, Scialdone A, Torres-Padilla ME. Iturbide A, et al. Among authors: schorpp k. Nat Struct Mol Biol. 2022 Mar;29(3):282. doi: 10.1038/s41594-022-00740-8. Nat Struct Mol Biol. 2022. PMID: 35165459 Free PMC article. No abstract available.
57 results