Selmecki A - Search Results

1

Single-cell detection of copy number changes reveals dynamic mechanisms of adaptation to antifungals in Candida albicans.

Zhou X, Hilk A, Solis NV, Scott N, Beach A, Soisangwan N, Billings CL, Burrack LS, Filler SG, Selmecki A. Zhou X, et al. Among authors: selmecki a. Nat Microbiol. 2024 Nov;9(11):2923-2938. doi: 10.1038/s41564-024-01795-7. Epub 2024 Sep 3. Nat Microbiol. 2024. PMID: 39227665

2

Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype.

Forche A, Solis NV, Swidergall M, Thomas R, Guyer A, Beach A, Cromie GA, Le GT, Lowell E, Pavelka N, Berman J, Dudley AM, Selmecki A, Filler SG. Forche A, et al. Among authors: selmecki a. PLoS Genet. 2019 May 15;15(5):e1008137. doi: 10.1371/journal.pgen.1008137. eCollection 2019 May. PLoS Genet. 2019. PMID: 31091232 Free PMC article.

3

Genomic Diversity across Candida auris Clinical Isolates Shapes Rapid Development of Antifungal Resistance In Vitro and In Vivo.

Burrack LS, Todd RT, Soisangwan N, Wiederhold NP, Selmecki A. Burrack LS, et al. Among authors: selmecki a. mBio. 2022 Aug 30;13(4):e0084222. doi: 10.1128/mbio.00842-22. Epub 2022 Jul 5. mBio. 2022. PMID: 35862787 Free PMC article.

4

The Dynamic Fungal Genome: Polyploidy, Aneuploidy and Copy Number Variation in Response to Stress.

Vande Zande P, Zhou X, Selmecki A. Vande Zande P, et al. Among authors: selmecki a. Annu Rev Microbiol. 2023 Sep 15;77:341-361. doi: 10.1146/annurev-micro-041320-112443. Epub 2023 Jun 12. Annu Rev Microbiol. 2023. PMID: 37307856 Free PMC article. Review.

5

Erg251 has complex and pleiotropic effects on azole susceptibility, filamentation, and stress response phenotypes.

Zhou X, Hilk A, Solis NV, Hogan BM, Bierbaum TA, Filler SG, Burrack LS, Selmecki A. Zhou X, et al. Among authors: selmecki a. bioRxiv [Preprint]. 2024 Mar 6:2024.03.06.583770. doi: 10.1101/2024.03.06.583770. bioRxiv. 2024. Update in: PLoS Pathog. 2024 Jul 30;20(7):e1012389. doi: 10.1371/journal.ppat.1012389. PMID: 38496635 Free PMC article. Updated. Preprint.

6

Erg251 has complex and pleiotropic effects on sterol composition, azole susceptibility, filamentation, and stress response phenotypes.

Zhou X, Hilk A, Solis NV, Pereira De Sa N, Hogan BM, Bierbaum TA, Del Poeta M, Filler SG, Burrack LS, Selmecki A. Zhou X, et al. Among authors: selmecki a. PLoS Pathog. 2024 Jul 30;20(7):e1012389. doi: 10.1371/journal.ppat.1012389. eCollection 2024 Jul. PLoS Pathog. 2024. PMID: 39078851 Free PMC article.

7

Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans.

Vande Zande P, Gautier C, Kawar N, Maufrais C, Metzner K, Wash E, Beach AK, Bracken R, Maciel EI, Pereira de Sá N, Fernandes CM, Solis NV, Del Poeta M, Filler SG, Berman J, Ene IV, Selmecki A. Vande Zande P, et al. Among authors: selmecki a. PLoS Pathog. 2024 Aug 30;20(8):e1012497. doi: 10.1371/journal.ppat.1012497. eCollection 2024 Aug. PLoS Pathog. 2024. PMID: 39213436 Free PMC article.

8

Antifungal Drug Concentration Impacts the Spectrum of Adaptive Mutations in Candida albicans.

Todd RT, Soisangwan N, Peters S, Kemp B, Crooks T, Gerstein A, Selmecki A. Todd RT, et al. Among authors: selmecki a. Mol Biol Evol. 2023 Jan 4;40(1):msad009. doi: 10.1093/molbev/msad009. Mol Biol Evol. 2023. PMID: 36649220 Free PMC article.

9

Rapid Evolution of Multidrug Resistance in a Candida lusitaniae Infection during Micafungin Monotherapy.

Scott NE, Edwin Erayil S, Kline SE, Selmecki A. Scott NE, et al. Among authors: selmecki a. Antimicrob Agents Chemother. 2023 Aug 17;67(8):e0054323. doi: 10.1128/aac.00543-23. Epub 2023 Jul 10. Antimicrob Agents Chemother. 2023. PMID: 37428075 Free PMC article.

10

Stress combined with loss of the Candida albicans SUMO protease Ulp2 triggers selection of aneuploidy via a two-step process.

Rizzo M, Soisangwan N, Vega-Estevez S, Price RJ, Uyl C, Iracane E, Shaw M, Soetaert J, Selmecki A, Buscaino A. Rizzo M, et al. Among authors: selmecki a. PLoS Genet. 2022 Dec 27;18(12):e1010576. doi: 10.1371/journal.pgen.1010576. eCollection 2022 Dec. PLoS Genet. 2022. PMID: 36574460 Free PMC article.

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