Baeuerle PA - Search Results

1

Intratumoral injection and retention hold promise to improve cytokine therapies for cancer.

Sauer K, Rakhra K, Wu K, Mehta NK, Michaelson JS, Baeuerle PA. Sauer K, et al. Among authors: baeuerle pa. Front Oncol. 2024 Aug 26;14:1456658. doi: 10.3389/fonc.2024.1456658. eCollection 2024. Front Oncol. 2024. PMID: 39252938 Free PMC article.

2

Engaging natural killer cells for cancer therapy via NKG2D, CD16A and other receptors.

Whalen KA, Rakhra K, Mehta NK, Steinle A, Michaelson JS, Baeuerle PA. Whalen KA, et al. Among authors: baeuerle pa. MAbs. 2023 Jan-Dec;15(1):2208697. doi: 10.1080/19420862.2023.2208697. MAbs. 2023. PMID: 37165468 Free PMC article. Review.

3

CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression.

Meetze K, Mehta NK, Li B, Michaelson JS, Baeuerle PA. Meetze K, et al. Among authors: baeuerle pa. J Immunother Cancer. 2023 Aug;11(8):e007398. doi: 10.1136/jitc-2023-007398. J Immunother Cancer. 2023. PMID: 37586770 Free PMC article.

4

CD19-directed T cell-engaging antibodies for the treatment of autoimmune disease.

Michaelson JS, Baeuerle PA. Michaelson JS, et al. Among authors: baeuerle pa. J Exp Med. 2024 May 6;221(5):e20240499. doi: 10.1084/jem.20240499. Epub 2024 Apr 8. J Exp Med. 2024. PMID: 38587494 Free PMC article.

5

CLN-617 Retains IL2 and IL12 in Injected Tumors to Drive Robust and Systemic Immune-Mediated Antitumor Activity.

Mehta NK, Rakhra K, Meetze KA, Li B, Momin N, Chang JYH, Wittrup KD, Baeuerle PA, Michaelson JS. Mehta NK, et al. Among authors: baeuerle pa. Cancer Immunol Res. 2024 Aug 1;12(8):1022-1038. doi: 10.1158/2326-6066.CIR-23-0636. Cancer Immunol Res. 2024. PMID: 38842347 Free PMC article.

6

Mesothelin-targeting T cells bearing a novel T cell receptor fusion construct (TRuC) exhibit potent antitumor efficacy against solid tumors.

Ding J, Guyette S, Schrand B, Geirut J, Horton H, Guo G, Delgoffe G, Menk A, Baeuerle PA, Hofmeister R, Tighe R. Ding J, et al. Among authors: baeuerle pa. Oncoimmunology. 2023 Feb 24;12(1):2182058. doi: 10.1080/2162402X.2023.2182058. eCollection 2023. Oncoimmunology. 2023. PMID: 36875551 Free PMC article.

7

Functional enhancement of mesothelin-targeted TRuC-T cells by a PD1-CD28 chimeric switch receptor.

McCarthy D, Lofgren M, Watt A, Horton H, Kieffer-Kwon P, Ding J, Kobold S, Baeuerle PA, Hofmeister R, Gutierrez DA, Tighe R. McCarthy D, et al. Among authors: baeuerle pa. Cancer Immunol Immunother. 2023 Dec;72(12):4195-4207. doi: 10.1007/s00262-023-03556-7. Epub 2023 Oct 18. Cancer Immunol Immunother. 2023. PMID: 37848682 Free PMC article.

8

T-cell-engaging antibodies for the treatment of solid tumors: challenges and opportunities.

Baeuerle PA, Wesche H. Baeuerle PA, et al. Curr Opin Oncol. 2022 Sep 1;34(5):552-558. doi: 10.1097/CCO.0000000000000869. Epub 2022 Jul 28. Curr Opin Oncol. 2022. PMID: 35880455 Free PMC article. Review.

9

A novel IgG-based FLT3xCD3 bispecific antibody for the treatment of AML and B-ALL.

Mehta NK, Pfluegler M, Meetze K, Li B, Sindel I, Vogt F, Marklin M, Heitmann JS, Kauer J, Osburg L, Zekri L, Bühring HJ, Mueller S, Hörner S, Baeuerle PA, Michaelson JS, Jung G, Salih HR. Mehta NK, et al. Among authors: baeuerle pa. J Immunother Cancer. 2022 Mar;10(3):e003882. doi: 10.1136/jitc-2021-003882. J Immunother Cancer. 2022. PMID: 35288466 Free PMC article.

10

Preclinical Characterization of HPN536, a Trispecific, T-Cell-Activating Protein Construct for the Treatment of Mesothelin-Expressing Solid Tumors.

Molloy ME, Austin RJ, Lemon BD, Aaron WH, Ganti V, Jones A, Jones SD, Strobel KL, Patnaik P, Sexton K, Tatalick L, Yu TZ, Baeuerle PA, Law CL, Wesche H. Molloy ME, et al. Among authors: baeuerle pa. Clin Cancer Res. 2021 Mar 1;27(5):1452-1462. doi: 10.1158/1078-0432.CCR-20-3392. Epub 2020 Dec 1. Clin Cancer Res. 2021. PMID: 33262134

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