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Prodrug activation in malaria parasites mediated by an imported erythrocyte esterase, acylpeptide hydrolase (APEH).
Sundararaman SA, Miller JJ, Daley EC, O'Brien KA, Kasak P, Daniels AM, Edwards RL, Heidel KM, Bague DA, Wilson MA, Koelper AJ, Kourtoglou EC, White AD, August SA, Apple GA, Rouamba RW, Durand AJ, Esteb JJ, Muller FL, Johnson RJ, Hoops GC, Dowd CS, Odom John AR. Sundararaman SA, et al. Among authors: daley ec. bioRxiv [Preprint]. 2024 Aug 31:2024.08.30.610542. doi: 10.1101/2024.08.30.610542. bioRxiv. 2024. PMID: 39257815 Free PMC article. Preprint.
Skipped wells and scientific error during fosfomycin agar dilution and broth microdilution lead to inconsistent minimal inhibitory concentrations and may be cause for reevaluating testing methods for Klebsiella pneumoniae.
Bixby ML, Daley EC, Collins LB, Salay JM, Bryson AL, Hirsch EB. Bixby ML, et al. Among authors: daley ec. Microbiol Spectr. 2024 Aug 6;12(8):e0420523. doi: 10.1128/spectrum.04205-23. Epub 2024 Jun 28. Microbiol Spectr. 2024. PMID: 38940588 Free PMC article.