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A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance.
Arriaga JM, Panja S, Alshalalfa M, Zhao J, Zou M, Giacobbe A, Madubata CJ, Kim JY, Rodriguez A, Coleman I, Virk RK, Hibshoosh H, Ertunc O, Ozbek B, Fountain J, Jeffrey Karnes R, Luo J, Antonarakis ES, Nelson PS, Feng FY, Rubin MA, De Marzo AM, Rabadan R, Sims PA, Mitrofanova A, Abate-Shen C. Arriaga JM, et al. Among authors: virk rk. Nat Cancer. 2020 Nov;1(11):1082-1096. doi: 10.1038/s43018-020-00125-0. Epub 2020 Oct 19. Nat Cancer. 2020. PMID: 34085047 Free PMC article.
Cooperation of loss of NKX3.1 and inflammation in prostate cancer initiation.
Le Magnen C, Virk RK, Dutta A, Kim JY, Panja S, Lopez-Bujanda ZA, Califano A, Drake CG, Mitrofanova A, Abate-Shen C. Le Magnen C, et al. Among authors: virk rk. Dis Model Mech. 2018 Nov 16;11(11):dmm035139. doi: 10.1242/dmm.035139. Dis Model Mech. 2018. PMID: 30266798 Free PMC article.
A Phase I Trial of Intravesical Cabazitaxel, Gemcitabine and Cisplatin for the Treatment of Nonmuscle Invasive bacillus Calmette-Guérin Unresponsive or Recurrent/Relapsing Urothelial Carcinoma of the Bladder.
DeCastro GJ, Sui W, Pak JS, Lee SM, Holder D, Kates MM, Virk RK, Drake CG, Anderson CB, James B, Abate-Shen CT, McKiernan JM. DeCastro GJ, et al. Among authors: virk rk. J Urol. 2020 Aug;204(2):247-253. doi: 10.1097/JU.0000000000000919. Epub 2020 Mar 2. J Urol. 2020. PMID: 32118506 Free PMC article. Clinical Trial.
NKX3.1 Localization to Mitochondria Suppresses Prostate Cancer Initiation.
Papachristodoulou A, Rodriguez-Calero A, Panja S, Margolskee E, Virk RK, Milner TA, Martina LP, Kim JY, Di Bernardo M, Williams AB, Maliza EA, Caputo JM, Haas C, Wang V, De Castro GJ, Wenske S, Hibshoosh H, McKiernan JM, Shen MM, Rubin MA, Mitrofanova A, Dutta A, Abate-Shen C. Papachristodoulou A, et al. Among authors: virk rk. Cancer Discov. 2021 Sep;11(9):2316-2333. doi: 10.1158/2159-8290.CD-20-1765. Epub 2021 Apr 23. Cancer Discov. 2021. PMID: 33893149 Free PMC article.
Co-clinical Analysis of a Genetically Engineered Mouse Model and Human Prostate Cancer Reveals Significance of NKX3.1 Expression for Response to 5α-reductase Inhibition.
Dutta A, Panja S, Virk RK, Kim JY, Zott R, Cremers S, Golombos DM, Liu D, Mosquera JM, Mostaghel EA, Barbieri CE, Mitrofanova A, Abate-Shen C. Dutta A, et al. Among authors: virk rk. Eur Urol. 2017 Oct;72(4):499-506. doi: 10.1016/j.eururo.2017.03.031. Epub 2017 Apr 4. Eur Urol. 2017. PMID: 28385453 Free PMC article.
52 results