Hill J - Search Results

1

Computationally Driven Discovery of a BCR-ABL1 Kinase Inhibitor with Activity in Multidrug-Resistant Chronic Myeloid Leukemia.

Hill J, Givhan RH, Yi B, Jones RM, Douglass EF, Xi Y, Schaefer HF 3rd, Crich D. Hill J, et al. J Med Chem. 2024 Oct 10;67(19):17820-17832. doi: 10.1021/acs.jmedchem.4c01852. Epub 2024 Sep 23. J Med Chem. 2024. PMID: 39311765 Free PMC article.

2

The N,N,O-Trisubstituted Hydroxylamine Isostere and Its Influence on Lipophilicity and Related Parameters.

Hill J, Crich D. Hill J, et al. ACS Med Chem Lett. 2022 Apr 20;13(5):799-806. doi: 10.1021/acsmedchemlett.1c00713. eCollection 2022 May 12. ACS Med Chem Lett. 2022. PMID: 35586423 Free PMC article.

3

Discovery of a Hydroxylamine-Based Brain-Penetrant EGFR Inhibitor for Metastatic Non-Small-Cell Lung Cancer.

Hill J, Jones RM, Crich D. Hill J, et al. J Med Chem. 2023 Nov 23;66(22):15477-15492. doi: 10.1021/acs.jmedchem.3c01669. Epub 2023 Nov 7. J Med Chem. 2023. PMID: 37934858 Free PMC article.

4

Atypical N-Alkyl to N-Noralkoxy Switch in a Dual cSRC/BCR-ABL1 Kinase Inhibitor Improves Drug Efflux and hERG Affinity.

Hill J, Jones RM, Crich D. Hill J, et al. ACS Med Chem Lett. 2023 Dec 5;14(12):1869-1875. doi: 10.1021/acsmedchemlett.3c00479. eCollection 2023 Dec 14. ACS Med Chem Lett. 2023. PMID: 38116407 Free PMC article.

5

Synthesis of O-tert-Butyl-N,N-disubstituted Hydroxylamines by N-O Bond Formation.

Hill J, Crich D. Hill J, et al. Org Lett. 2021 Aug 20;23(16):6396-6400. doi: 10.1021/acs.orglett.1c02215. Epub 2021 Jul 30. Org Lett. 2021. PMID: 34328741

6

Recent Advances in the Synthesis of Di- and Trisubstituted Hydroxylamines.

Hill J, Beckler TD, Crich D. Hill J, et al. Molecules. 2023 Mar 21;28(6):2816. doi: 10.3390/molecules28062816. Molecules. 2023. PMID: 36985788 Free PMC article. Review.

7

Diversity-Oriented Synthesis of N,N,O-Trisubstituted Hydroxylamines from Alcohols and Amines by N-O Bond Formation.

Hill J, Hettikankanamalage AA, Crich D. Hill J, et al. J Am Chem Soc. 2020 Sep 2;142(35):14820-14825. doi: 10.1021/jacs.0c05991. Epub 2020 Aug 24. J Am Chem Soc. 2020. PMID: 32803971

8

Exploring Noncovalent Protease Inhibitors for the Treatment of Severe Acute Respiratory Syndrome and Severe Acute Respiratory Syndrome-Like Coronaviruses.

Freitas BT, Ahiadorme DA, Bagul RS, Durie IA, Ghosh S, Hill J, Kramer NE, Murray J, O'Boyle BM, Onobun E, Pirrone MG, Shepard JD, Enos S, Subedi YP, Upadhyaya K, Tripp RA, Cummings BS, Crich D, Pegan SD. Freitas BT, et al. Among authors: hill j. ACS Infect Dis. 2022 Mar 11;8(3):596-611. doi: 10.1021/acsinfecdis.1c00631. Epub 2022 Feb 24. ACS Infect Dis. 2022. PMID: 35199517 Free PMC article.

9

Dietary interventions in autism: a critical appraisal and commentary on the findings of a systematic review.

Woods S, Doherty A, Hill J. Woods S, et al. Among authors: hill j. Br J Neurosci Nurs. 2024 Aug 2;20(4):142-147. doi: 10.12968/bjnn.2024.0035. Br J Neurosci Nurs. 2024. PMID: 39555178 Free PMC article.

10

Gestational Diabetes Mellitus Prevention: A Commentary.

Gallagher C, Hill J. Gallagher C, et al. Among authors: hill j. Pract Midwife. 2024 Sep 1;27(5):24-28. doi: 10.55975/TPDP7486. Pract Midwife. 2024. PMID: 39555125 Free PMC article.

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