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Page 1
The tyrosine kinase Yes1 is a druggable host factor of HEV.
Haase JA, Baheerathan A, Zhang X, Fu RM, Nocke MK, Decker C, Dao Thi VL, Todt D, Neyts J, Kaptein SJF, Steinmann E, Kinast V. Haase JA, et al. Among authors: nocke mk. Hepatol Commun. 2024 Oct 17;8(11):e0553. doi: 10.1097/HC9.0000000000000553. eCollection 2024 Nov 1. Hepatol Commun. 2024. PMID: 39560373
Divergent autoantibody and cytokine levels in COVID-19 sepsis patients influence survival.
Kühn D, Heinen N, Sutter K, Herrmann ST, Nocke MK, Todt D, Burbelo PD, Steinmann E, Ziehe D, Koos B, Adamzik M, Putensen C, Zarbock A, Gravemann U, Jork C, Pfaender S; SepsisDataNet.NRW and CovidDataNet.NRW research group. Kühn D, et al. Among authors: nocke mk. J Med Virol. 2024 Oct;96(10):e29935. doi: 10.1002/jmv.29935. J Med Virol. 2024. PMID: 39323094
MicroRNAs modulate SARS-CoV-2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2.
Khanal R, Heinen N, Bogomolova A, Meister TL, Herrmann ST, Westhoven S, Nocke MK, Todt D, Jockenhövel F, Klein IM, Hartmann L, Vondran FWR, Steinmann E, Zimmer G, Ott M, Brown RJP, Sharma AD, Pfaender S. Khanal R, et al. Among authors: nocke mk. Liver Int. 2024 Nov;44(11):2983-2995. doi: 10.1111/liv.16079. Epub 2024 Aug 22. Liver Int. 2024. PMID: 39175256 Free article.
Genetic determinants of host- and virus-derived insertions for hepatitis E virus replication.
Wißing MH, Meister TL, Nocke MK, Gömer A, Masovic M, Knegendorf L, Brüggemann Y, Bader V, Siddharta A, Bock CT, Ploss A, Kenney SP, Winklhofer KF, Behrendt P, Wedemeyer H, Steinmann E, Todt D. Wißing MH, et al. Among authors: nocke mk. Nat Commun. 2024 Jun 6;15(1):4855. doi: 10.1038/s41467-024-49219-8. Nat Commun. 2024. PMID: 38844458 Free PMC article.
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution.
Qu B, Miskey C, Gömer A, Kleinert RDV, Ibanez SC, Eberle R, Ebenig A, Postmus D, Nocke MK, Herrmann M, Itotia TK, Herrmann ST, Heinen N, Höck S, Hastert FD, von Rhein C, Schürmann C, Li X, van Zandbergen G, Widera M, Ciesek S, Schnierle BS, Tarr AW, Steinmann E, Goffinet C, Pfaender S, Locker JK, Mühlebach MD, Todt D, Brown RJP. Qu B, et al. Among authors: nocke mk. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2407437121. doi: 10.1073/pnas.2407437121. Epub 2024 May 30. Proc Natl Acad Sci U S A. 2024. PMID: 38814864 Free PMC article.
Targeting cellular cathepsins inhibits hepatitis E virus entry.
Klöhn M, Burkard T, Janzen J, Haase JA, Gömer A, Fu R, Ssebyatika G, Nocke MK, Brown RJP, Krey T, Dao Thi VL, Kinast V, Brüggemann Y, Todt D, Steinmann E. Klöhn M, et al. Among authors: nocke mk. Hepatology. 2024 Nov 1;80(5):1239-1251. doi: 10.1097/HEP.0000000000000912. Epub 2024 May 10. Hepatology. 2024. PMID: 38728662 Free PMC article.
The International Virus Bioinformatics Meeting 2023.
Hufsky F, Abecasis AB, Babaian A, Beck S, Brierley L, Dellicour S, Eggeling C, Elena SF, Gieraths U, Ha AD, Harvey W, Jones TC, Lamkiewicz K, Lovate GL, Lücking D, Machyna M, Nishimura L, Nocke MK, Renard BY, Sakaguchi S, Sakellaridi L, Spangenberg J, Tarradas-Alemany M, Triebel S, Vakulenko Y, Wijesekara RY, González-Candelas F, Krautwurst S, Pérez-Cataluña A, Randazzo W, Sánchez G, Marz M. Hufsky F, et al. Among authors: nocke mk. Viruses. 2023 Sep 30;15(10):2031. doi: 10.3390/v15102031. Viruses. 2023. PMID: 37896809 Free PMC article.
Emergence of resistance-associated variants during sofosbuvir treatment in chronically infected hepatitis E patients.
Gömer A, Klöhn M, Jagst M, Nocke MK, Pischke S, Horvatits T, Schulze Zur Wiesch J, Müller T, Hardtke S, Cornberg M, Wedemeyer H, Behrendt P, Steinmann E, Todt D. Gömer A, et al. Among authors: nocke mk. Hepatology. 2023 Dec 1;78(6):1882-1895. doi: 10.1097/HEP.0000000000000514. Epub 2023 Jun 20. Hepatology. 2023. PMID: 37334496 Free PMC article.
13 results