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Cell-targeted gene modification by delivery of CRISPR-Cas9 ribonucleoprotein complexes in pseudotyped lentivirus-derived nanoparticles.
Nielsen IH, Rovsing AB, Janns JH, Thomsen EA, Ruzo A, Bøggild A, Nedergaard F, Møller CT, Boesen T, Degn SE, Shah JV, Mikkelsen JG. Nielsen IH, et al. Among authors: degn se. Mol Ther Nucleic Acids. 2024 Aug 31;35(4):102318. doi: 10.1016/j.omtn.2024.102318. eCollection 2024 Dec 10. Mol Ther Nucleic Acids. 2024. PMID: 39329149 Free PMC article.
STING activation counters glioblastoma by vascular alteration and immune surveillance.
Joseph JV, Blaavand MS, Cai H, Vernejoul F, Knopper RW, Lindhardt TB, Skipper KA, Axelgaard E, Reinert L, Mikkelsen JG, Borghammer P, Degn SE, Perouzel E, Hager H, Hansen B, Kalucka JM, Vendelbo M, Paludan SR, Thomsen MK. Joseph JV, et al. Among authors: degn se. Cancer Lett. 2023 Nov 28;579:216480. doi: 10.1016/j.canlet.2023.216480. Epub 2023 Nov 4. Cancer Lett. 2023. PMID: 37931834 Free article.
Antigen presentation by B cells enables epitope spreading across an MHC barrier.
Fahlquist-Hagert C, Wittenborn TR, Terczyńska-Dyla E, Kastberg KS, Yang E, Rallistan AN, Markett QR, Winther G, Fonager S, Voss LF, Pedersen MK, van Campen N, Ferapontov A, Jensen L, Huang J, Nieland JD, van der Poel CE, Palmfeldt J, Carroll MC, Utz PJ, Luo Y, Lin L, Degn SE. Fahlquist-Hagert C, et al. Among authors: degn se. Nat Commun. 2023 Oct 31;14(1):6941. doi: 10.1038/s41467-023-42541-7. Nat Commun. 2023. PMID: 37907556 Free PMC article.
Haplosufficiency of MHCII in autoreactive germinal center B cells.
Fahlquist-Hagert C, Wittenborn TR, Ferapontov A, Jensen L, Terczyńska-Dyla E, Degn SE. Fahlquist-Hagert C, et al. Among authors: degn se. Eur J Immunol. 2024 Jan;54(1):e2350422. doi: 10.1002/eji.202350422. Epub 2023 Nov 9. Eur J Immunol. 2024. PMID: 37873698
Antigen footprint governs activation of the B cell receptor.
Ferapontov A, Omer M, Baudrexel I, Nielsen JS, Dupont DM, Juul-Madsen K, Steen P, Eklund AS, Thiel S, Vorup-Jensen T, Jungmann R, Kjems J, Degn SE. Ferapontov A, et al. Among authors: degn se. Nat Commun. 2023 Feb 22;14(1):976. doi: 10.1038/s41467-023-36672-0. Nat Commun. 2023. PMID: 36813795 Free PMC article.
47 results