Raschke M - Search Results

1

Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T-Cell Immunity against Cancer.

Mowat J, Carretero R, Leder G, Aiguabella Font N, Neuhaus R, Berndt S, Günther J, Friberg A, Schäfer M, Briem H, Raschke M, Miyatake Ondozabal H, Buchmann B, Boemer U, Kreft B, Hartung IV, Offringa R. Mowat J, et al. Among authors: raschke m. J Med Chem. 2024 Oct 10;67(19):17429-17453. doi: 10.1021/acs.jmedchem.4c01325. Epub 2024 Sep 27. J Med Chem. 2024. PMID: 39331123 Free PMC article.

2

New Generation of sGC Stimulators: Discovery of Imidazo[1,2-a]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Resistant Hypertension.

Vakalopoulos A, Wunder F, Hartung IV, Redlich G, Jautelat R, Buchgraber P, Hassfeld J, Gromov AV, Lindner N, Bierer D, Gries J, Kroh W, Paulsen H, Mittendorf J, Lang D, Becker-Pelster E, Brockschnieder D, Geiss V, Li V, Straub A, Knorr A, Mondritzki T, Trübel H, Raschke M, Schaefer M, Thomas D, Sandner P, Stasch JP, Follmann M. Vakalopoulos A, et al. Among authors: raschke m. J Med Chem. 2023 Jun 8;66(11):7280-7303. doi: 10.1021/acs.jmedchem.2c02082. Epub 2023 Apr 11. J Med Chem. 2023. PMID: 37040336

3

Quantitative Systems Toxicology Identifies Independent Mechanisms for Hepatotoxicity and Bilirubin Elevations Due to AKR1C3 Inhibitor BAY1128688.

Battista C, Shoda LKM, Watkins PB, Groettrup-Wolfers E, Rottmann A, Raschke M, Generaux GT. Battista C, et al. Among authors: raschke m. Clin Pharmacol Ther. 2023 Nov;114(5):1023-1032. doi: 10.1002/cpt.3010. Epub 2023 Aug 10. Clin Pharmacol Ther. 2023. PMID: 37501650

4

The Effect of C-Arm Position on Femoral Tunnel Placement in Medial Patellofemoral Ligament Reconstruction.

Thürig G, Herbst E, Deichsel A, Peez C, Briese T, Glasbrenner J, Raschke MJ, Kittl C. Thürig G, et al. Among authors: raschke mj. Orthop J Sports Med. 2024 Nov 8;12(11):23259671241288153. doi: 10.1177/23259671241288153. eCollection 2024 Nov. Orthop J Sports Med. 2024. PMID: 39525352 Free PMC article.

5

Anterior Slope-Modifying Osteotomies Alter the Length Change Behavior of the Superficial Medial Collateral Ligament: A Biomechanical Study.

Peez C, Ottens C, Deichsel A, Raschke MJ, Briese T, Herbst E, Robinson JR, Kittl C. Peez C, et al. Among authors: raschke mj. Am J Sports Med. 2024 Nov;52(13):3277-3285. doi: 10.1177/03635465241280985. Epub 2024 Oct 6. Am J Sports Med. 2024. PMID: 39370699 Free PMC article.

6

Targeting Pseudomonas aeruginosa biofilm with an evolutionary trained bacteriophage cocktail exploiting phage resistance trade-offs.

Kunisch F, Campobasso C, Wagemans J, Yildirim S, Chan BK, Schaudinn C, Lavigne R, Turner PE, Raschke MJ, Trampuz A, Gonzalez Moreno M. Kunisch F, et al. Among authors: raschke mj. Nat Commun. 2024 Oct 3;15(1):8572. doi: 10.1038/s41467-024-52595-w. Nat Commun. 2024. PMID: 39362854 Free PMC article.

7

A Flat Reconstruction of the Medial Collateral Ligament and Anteromedial Structures Restores Native Knee Kinematics: A Biomechanical Robotic Investigation.

Deichsel A, Peez C, Raschke MJ, Albert A, Herbort M, Kittl C, Fink C, Herbst E. Deichsel A, et al. Among authors: raschke mj. Am J Sports Med. 2024 Nov;52(13):3306-3313. doi: 10.1177/03635465241280984. Epub 2024 Oct 3. Am J Sports Med. 2024. PMID: 39360333 Free PMC article.

8

Specific fibre areas in the femoral footprint of the posterior cruciate ligament act as a major contributor in resisting posterior tibial displacement: A biomechanical robotic investigation.

Deichsel A, Briese T, Liu W, Raschke MJ, Albert A, Peez C, Weiler A, Kittl C. Deichsel A, et al. Among authors: raschke mj. Knee Surg Sports Traumatol Arthrosc. 2024 Sep 26. doi: 10.1002/ksa.12486. Online ahead of print. Knee Surg Sports Traumatol Arthrosc. 2024. PMID: 39327853

9

Improving the Care of Severe, Open Fractures and Postoperative Infections of the Lower Extremities: Protocol for an Interdisciplinary Treatment Approach.

Rosslenbroich S, Laumann M, Hasebrook J, Rodde S, Grosser J, Greiner W, Hirsch T, Windrich S, Raschke MJ. Rosslenbroich S, et al. Among authors: raschke mj. JMIR Res Protoc. 2024 Sep 16;13:e57820. doi: 10.2196/57820. JMIR Res Protoc. 2024. PMID: 39284180 Free PMC article.

10

Arthroscopic Centralization of the Medial Meniscus Reduces Load on a Posterior Root Repair Under Dynamic Varus Loading: A Biomechanical Investigation.

Deichsel A, Peez C, Raschke MJ, Richards RG, Gueorguiev B, Zderic I, Herbst E, Kittl C. Deichsel A, et al. Among authors: raschke mj. Am J Sports Med. 2024 Oct;52(12):3030-3038. doi: 10.1177/03635465241274791. Epub 2024 Sep 15. Am J Sports Med. 2024. PMID: 39279271 Free PMC article.

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