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Base editing of the HBG promoter induces potent fetal hemoglobin expression with no detectable off-target mutations in human HSCs.
Han W, Qiu HY, Sun S, Fu ZC, Wang GQ, Qian X, Wang L, Zhai X, Wei J, Wang Y, Guo YL, Cao GH, Ji RJ, Zhang YZ, Ma H, Wang H, Zhao M, Wu J, Bi L, Chen QB, Li Z, Yu L, Mou X, Yin H, Yang L, Chen J, Yang B, Zhang Y. Han W, et al. Among authors: yin h. Cell Stem Cell. 2023 Dec 7;30(12):1624-1639.e8. doi: 10.1016/j.stem.2023.10.007. Epub 2023 Nov 20. Cell Stem Cell. 2023. PMID: 37989316
Characterization of a thermostable Cas12a ortholog.
Wu J, Gao P, Shi Y, Zhang C, Tong X, Fan H, Zhou X, Zhang Y, Yin H. Wu J, et al. Among authors: yin h. Cell Insight. 2023 Oct 11;2(6):100126. doi: 10.1016/j.cellin.2023.100126. eCollection 2023 Dec. Cell Insight. 2023. PMID: 38047138 Free PMC article.
Cas12a-based one-pot SNP detection with high accuracy.
Zhang HX, Zhang C, Lu S, Tong X, Zhang K, Yin H, Zhang Y. Zhang HX, et al. Among authors: yin h. Cell Insight. 2023 Feb 1;2(2):100080. doi: 10.1016/j.cellin.2023.100080. eCollection 2023 Apr. Cell Insight. 2023. PMID: 37193068 Free PMC article.
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