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Page 1
Combined Inhibition of MNK Signaling and BET Proteins Reveals TGM2 as a Novel Vulnerability in Melanoma.
Méant A, Moussa O, Lebeau B, Gonçalves C, Richard VR, Cai F, Prabhu SA, Langke M, Guettler EM, Su J, Gagnon N, Zahedi RP, Borchers CH, Miller WH Jr, Del Rincón SV, Witcher M. Méant A, et al. Among authors: borchers ch. J Invest Dermatol. 2024 Oct 1:S0022-202X(24)02160-2. doi: 10.1016/j.jid.2024.07.037. Online ahead of print. J Invest Dermatol. 2024. PMID: 39357785 Free article. No abstract available.
FGF1 supports glycolytic metabolism through the estrogen receptor in endocrine-resistant and obesity-associated breast cancer.
Castillo-Castrejon M, Sankofi BM, Murguia SJ, Udeme AA, Cen HH, Xia YH, Thomas NS, Berry WL, Jones KL, Richard VR, Zahedi RP, Borchers CH, Johnson JD, Wellberg EA. Castillo-Castrejon M, et al. Among authors: borchers ch. Breast Cancer Res. 2023 Aug 22;25(1):99. doi: 10.1186/s13058-023-01699-0. Breast Cancer Res. 2023. PMID: 37608351 Free PMC article.
Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation.
Zhang AMY, Xia YH, Lin JSH, Chu KH, Wang WCK, Ruiter TJJ, Yang JCC, Chen N, Chhuor J, Patil S, Cen HH, Rideout EJ, Richard VR, Schaeffer DF, Zahedi RP, Borchers CH, Johnson JD, Kopp JL. Zhang AMY, et al. Among authors: borchers ch. Cell Metab. 2023 Dec 5;35(12):2119-2135.e5. doi: 10.1016/j.cmet.2023.10.003. Epub 2023 Oct 31. Cell Metab. 2023. PMID: 37913768
The E3 ubiquitin ligase Nedd4L preserves skeletal muscle stem cell quiescence by inhibiting their activation.
Blackburn DM, Sahinyan K, Hernández-Corchado A, Lazure F, Richard V, Raco L, Perron G, Zahedi RP, Borchers CH, Lepper C, Kawabe H, Jahani-Asl A, Najafabadi HS, Soleimani VD. Blackburn DM, et al. Among authors: borchers ch. iScience. 2024 Jun 11;27(7):110241. doi: 10.1016/j.isci.2024.110241. eCollection 2024 Jul 19. iScience. 2024. PMID: 39015146 Free PMC article.
Universal method for the isolation of microvessels from frozen brain tissue: A proof-of-concept multiomic investigation of the neurovasculature.
Wakid M, Almeida D, Aouabed Z, Rahimian R, Davoli MA, Yerko V, Leonova-Erko E, Richard V, Zahedi R, Borchers C, Turecki G, Mechawar N. Wakid M, et al. Brain Behav Immun Health. 2023 Sep 21;34:100684. doi: 10.1016/j.bbih.2023.100684. eCollection 2023 Dec. Brain Behav Immun Health. 2023. PMID: 37822873 Free PMC article.
The Deubiquitylase Otub1 Regulates the Chemotactic Response of Splenic B Cells by Modulating the Stability of the γ-Subunit Gng2.
Luo VM, Shen C, Worme S, Bhagrath A, Simo-Cheyou E, Findlay S, Hébert S, Wai Lam Poon W, Aryanpour Z, Zhang T, Zahedi RP, Boulais J, Buchwald ZS, Borchers CH, Côté JF, Kleinman CL, Mandl JN, Orthwein A. Luo VM, et al. Among authors: borchers ch. Mol Cell Biol. 2024 Jan;44(1):1-16. doi: 10.1080/10985549.2023.2290434. Epub 2024 Jan 29. Mol Cell Biol. 2024. PMID: 38270191
345 results