Yen HY - Search Results

1

Coupling and Activation of the β1 Adrenergic Receptor - The Role of the Third Intracellular Loop.

Qiu X, Chao K, Song S, Wang YQ, Chen YA, Rouse SL, Yen HY, Robinson CV. Qiu X, et al. Among authors: yen hy. J Am Chem Soc. 2024 Oct 3;146(41):28527-37. doi: 10.1021/jacs.4c11250. Online ahead of print. J Am Chem Soc. 2024. PMID: 39359104 Free PMC article.

2

Ligand binding to a G protein-coupled receptor captured in a mass spectrometer.

Yen HY, Hopper JTS, Liko I, Allison TM, Zhu Y, Wang D, Stegmann M, Mohammed S, Wu B, Robinson CV. Yen HY, et al. Sci Adv. 2017 Jun 16;3(6):e1701016. doi: 10.1126/sciadv.1701016. eCollection 2017 Jun. Sci Adv. 2017. PMID: 28630934 Free PMC article.

3

Native Desorption Electrospray Ionization Liberates Soluble and Membrane Protein Complexes from Surfaces.

Ambrose S, Housden NG, Gupta K, Fan J, White P, Yen HY, Marcoux J, Kleanthous C, Hopper JTS, Robinson CV. Ambrose S, et al. Among authors: yen hy. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14463-14468. doi: 10.1002/anie.201704849. Epub 2017 Sep 18. Angew Chem Int Ed Engl. 2017. PMID: 28884954 Free PMC article.

4

PtdIns(4,5)P₂ stabilizes active states of GPCRs and enhances selectivity of G-protein coupling.

Yen HY, Hoi KK, Liko I, Hedger G, Horrell MR, Song W, Wu D, Heine P, Warne T, Lee Y, Carpenter B, Plückthun A, Tate CG, Sansom MSP, Robinson CV. Yen HY, et al. Nature. 2018 Jul;559(7714):423-427. doi: 10.1038/s41586-018-0325-6. Epub 2018 Jul 11. Nature. 2018. PMID: 29995853 Free PMC article.

5

An electron transfer path connects subunits of a mycobacterial respiratory supercomplex.

Gong H, Li J, Xu A, Tang Y, Ji W, Gao R, Wang S, Yu L, Tian C, Li J, Yen HY, Man Lam S, Shui G, Yang X, Sun Y, Li X, Jia M, Yang C, Jiang B, Lou Z, Robinson CV, Wong LL, Guddat LW, Sun F, Wang Q, Rao Z. Gong H, et al. Among authors: yen hy. Science. 2018 Nov 30;362(6418):eaat8923. doi: 10.1126/science.aat8923. Epub 2018 Oct 25. Science. 2018. PMID: 30361386

6

State-dependent Lipid Interactions with the A2a Receptor Revealed by MD Simulations Using In Vivo-Mimetic Membranes.

Song W, Yen HY, Robinson CV, Sansom MSP. Song W, et al. Among authors: yen hy. Structure. 2019 Feb 5;27(2):392-403.e3. doi: 10.1016/j.str.2018.10.024. Epub 2018 Dec 20. Structure. 2019. PMID: 30581046 Free PMC article.

7

Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors.

Urner LH, Liko I, Yen HY, Hoi KK, Bolla JR, Gault J, Almeida FG, Schweder MP, Shutin D, Ehrmann S, Haag R, Robinson CV, Pagel K. Urner LH, et al. Among authors: yen hy. Nat Commun. 2020 Jan 28;11(1):564. doi: 10.1038/s41467-020-14424-8. Nat Commun. 2020. PMID: 31992701 Free PMC article.

8

Correlating Glycoforms of DC-SIGN with Stability Using a Combination of Enzymatic Digestion and Ion Mobility Mass Spectrometry.

Yen HY, Liko I, Gault J, Wu D, Struwe WB, Robinson CV. Yen HY, et al. Angew Chem Int Ed Engl. 2020 Sep 1;59(36):15560-15564. doi: 10.1002/anie.202005727. Epub 2020 Jul 7. Angew Chem Int Ed Engl. 2020. PMID: 33462887 Free PMC article.

9

Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization.

Bada Juarez JF, Judge PJ, Adam S, Axford D, Vinals J, Birch J, Kwan TOC, Hoi KK, Yen HY, Vial A, Milhiet PE, Robinson CV, Schapiro I, Moraes I, Watts A. Bada Juarez JF, et al. Among authors: yen hy. Nat Commun. 2021 Jan 27;12(1):629. doi: 10.1038/s41467-020-20596-0. Nat Commun. 2021. PMID: 33504778 Free PMC article.

10

Structural insights into the lipid and ligand regulation of serotonin receptors.

Xu P, Huang S, Zhang H, Mao C, Zhou XE, Cheng X, Simon IA, Shen DD, Yen HY, Robinson CV, Harpsøe K, Svensson B, Guo J, Jiang H, Gloriam DE, Melcher K, Jiang Y, Zhang Y, Xu HE. Xu P, et al. Among authors: yen hy. Nature. 2021 Apr;592(7854):469-473. doi: 10.1038/s41586-021-03376-8. Epub 2021 Mar 24. Nature. 2021. PMID: 33762731

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