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Page 1
Genetic analysis of cognitive preservation in the midwestern Amish reveals a novel locus on chromosome 2.
Main LR, Song YE, Lynn A, Laux RA, Miskimen KL, Osterman MD, Cuccaro ML, Ogrocki PK, Lerner AJ, Vance JM, Fuzzell D, Fuzzell SL, Hochstetler SD, Dorfsman DA, Caywood LJ, Prough MB, Adams LD, Clouse JE, Herington SD, Scott WK, Pericak-Vance MA, Haines JL. Main LR, et al. Among authors: osterman md. Alzheimers Dement. 2024 Nov;20(11):7453-7464. doi: 10.1002/alz.14045. Epub 2024 Oct 8. Alzheimers Dement. 2024. PMID: 39376159 Free PMC article.
Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets.
Ramos J, Caywood LJ, Prough MB, Clouse JE, Herington SD, Slifer SH, Fuzzell MD, Fuzzell SL, Hochstetler SD, Miskimen KL, Main LR, Osterman MD, Zaman AF, Whitehead PL, Adams LD, Laux RA, Song YE, Foroud TM, Mayeux RP, St George-Hyslop P, Ogrocki PK, Lerner AJ, Vance JM, Cuccaro ML, Haines JL, Pericak-Vance MA, Scott WK. Ramos J, et al. Among authors: osterman md. Alzheimers Dement. 2023 Feb;19(2):611-620. doi: 10.1002/alz.12686. Epub 2022 May 1. Alzheimers Dement. 2023. PMID: 35490390 Free PMC article.
The genetic architecture of Alzheimer disease risk in the Ohio and Indiana Amish.
Osterman MD, Song YE, Adams LD, Laux RA, Caywood LJ, Prough MB, Clouse JE, Herington SD, Slifer SH, Lynn A, Fuzzell MD, Fuzzell SL, Hochstetler SD, Miskimen K, Main LR, Dorfsman DA, Ogrocki P, Lerner AJ, Ramos J, Vance JM, Cuccaro ML, Scott WK, Pericak-Vance MA, Haines JL. Osterman MD, et al. HGG Adv. 2022 Apr 27;3(3):100114. doi: 10.1016/j.xhgg.2022.100114. eCollection 2022 Jul 14. HGG Adv. 2022. PMID: 35599847 Free PMC article.
Visuospatial and Verbal Memory Differences in Amish Individuals With Alzheimer Disease and Related Dementias.
Prough MB, Zaman A, Caywood LJ, Clouse JE, Herington SD, Slifer SH, Dorfsman DA, Adams LA, Laux RA, Song YE, Lynn A, Fuzzell D, Fuzzell SL, Miller SD, Miskimen K, Main LR, Osterman MD, Ogrocki P, Lerner AJ, Vance JM, Haines JL, Scott WK, Pericak-Vance M, Cuccaro ML. Prough MB, et al. Among authors: osterman md. Alzheimer Dis Assoc Disord. 2023 Jul-Sep 01;37(3):195-199. doi: 10.1097/WAD.0000000000000570. Epub 2023 Aug 2. Alzheimer Dis Assoc Disord. 2023. PMID: 37561946 Free PMC article.
Founder population-specific weights yield improvements in performance of polygenic risk scores for Alzheimer disease in the Midwestern Amish.
Osterman MD, Song YE, Lynn A, Miskimen K, Adams LD, Laux RA, Caywood LJ, Prough MB, Clouse JE, Herington SD, Slifer SH, Fuzzell SL, Hochstetler SD, Main LR, Dorfsman DA, Zaman AF, Ogrocki P, Lerner AJ, Vance JM, Cuccaro ML, Scott WK, Pericak-Vance MA, Haines JL. Osterman MD, et al. HGG Adv. 2023 Oct 12;4(4):100241. doi: 10.1016/j.xhgg.2023.100241. Epub 2023 Sep 22. HGG Adv. 2023. PMID: 37742071 Free PMC article.
Polygenic Risk Scores.
Osterman MD, Kinzy TG, Bailey JNC. Osterman MD, et al. Curr Protoc. 2021 May;1(5):e126. doi: 10.1002/cpz1.126. Curr Protoc. 2021. PMID: 33987971
Tissue specificity of DNA damage response and tumorigenesis.
Sun S, Osterman MD, Li M. Sun S, et al. Among authors: osterman md. Cancer Biol Med. 2019 Aug;16(3):396-414. doi: 10.20892/j.issn.2095-3941.2019.0097. Cancer Biol Med. 2019. PMID: 31565474 Free PMC article.
Genetic analysis of cognitive preservation in the midwestern Amish reveals a novel locus on chromosome 2.
Main LR, Song YE, Lynn A, Laux RA, Miskimen KL, Osterman MD, Cuccaro ML, Ogrocki PK, Lerner AJ, Vance JM, Fuzzell MD, Fuzzell SL, Hochstetler SD, Dorfsman DA, Caywood LJ, Prough MB, Adams LD, Clouse JE, Herington SD, Scott WK, Pericak-Vance MA, Haines JL. Main LR, et al. Among authors: osterman md. medRxiv [Preprint]. 2023 Dec 14:2023.12.13.23299932. doi: 10.1101/2023.12.13.23299932. medRxiv. 2023. Update in: Alzheimers Dement. 2024 Nov;20(11):7453-7464. doi: 10.1002/alz.14045. PMID: 38168325 Free PMC article. Updated. Preprint.