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The use of a multi-metric readout screen to identify EHMT2/G9a-inhibition as a modulator of cancer-associated fibroblast activation state.
Wu NC, Quevedo R, Nurse M, Hezaveh K, Liu H, Sun F, Muffat J, Sun Y, Simmons CA, McGaha TL, Prinos P, Arrowsmith CH, Ailles L, D'Arcangelo E, McGuigan AP. Wu NC, et al. Among authors: simmons ca. Biomaterials. 2025 Mar;314:122879. doi: 10.1016/j.biomaterials.2024.122879. Epub 2024 Oct 5. Biomaterials. 2025. PMID: 39395244 Free article.
(Micro)managing the mechanical microenvironment.
Moraes C, Sun Y, Simmons CA. Moraes C, et al. Among authors: simmons ca. Integr Biol (Camb). 2011 Oct;3(10):959-71. doi: 10.1039/c1ib00056j. Epub 2011 Sep 19. Integr Biol (Camb). 2011. PMID: 21931883 Review.
228 results