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Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2.
Scott DC, Dharuman S, Griffith E, Chai SC, Ronnebaum J, King MT, Tangallapally R, Lee C, Gee CT, Yang L, Li Y, Loudon VC, Lee HW, Ochoada J, Miller DJ, Jayasinghe T, Paulo JA, Elledge SJ, Harper JW, Chen T, Lee RE, Schulman BA. Scott DC, et al. Among authors: chen t. Nat Commun. 2024 Oct 12;15(1):8829. doi: 10.1038/s41467-024-52966-3. Nat Commun. 2024. PMID: 39396041 Free PMC article.
Role of CAR and PXR in xenobiotic sensing and metabolism.
Wang YM, Ong SS, Chai SC, Chen T. Wang YM, et al. Among authors: chen t. Expert Opin Drug Metab Toxicol. 2012 Jul;8(7):803-17. doi: 10.1517/17425255.2012.685237. Epub 2012 May 3. Expert Opin Drug Metab Toxicol. 2012. PMID: 22554043 Free PMC article. Review.
Metabolic activation of CaMKII by coenzyme A.
McCoy F, Darbandi R, Lee HC, Bharatham K, Moldoveanu T, Grace CR, Dodd K, Lin W, Chen SI, Tangallapally RP, Kurokawa M, Lee RE, Shelat AA, Chen T, Green DR, Harris RA, Lin SH, Fissore RA, Colbran RJ, Nutt LK. McCoy F, et al. Among authors: chen si, chen t. Mol Cell. 2013 Nov 7;52(3):325-39. doi: 10.1016/j.molcel.2013.08.043. Epub 2013 Oct 3. Mol Cell. 2013. PMID: 24095281 Free PMC article.
Pregnane X receptor and drug-induced liver injury.
Wang YM, Chai SC, Brewer CT, Chen T. Wang YM, et al. Among authors: chen t. Expert Opin Drug Metab Toxicol. 2014 Nov;10(11):1521-32. doi: 10.1517/17425255.2014.963555. Epub 2014 Sep 25. Expert Opin Drug Metab Toxicol. 2014. PMID: 25252616 Free PMC article. Review.
Small-molecule modulators of the constitutive androstane receptor.
Cherian MT, Chai SC, Chen T. Cherian MT, et al. Among authors: chen t. Expert Opin Drug Metab Toxicol. 2015 Jul;11(7):1099-114. doi: 10.1517/17425255.2015.1043887. Epub 2015 May 15. Expert Opin Drug Metab Toxicol. 2015. PMID: 25979168 Free PMC article. Review.
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