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Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates.
Rajagopalan S, Rourke AK, Asare E, Kohlerschmidt DJ, Das L, Ngema SL, Mulholland CV, Vilchèze C, Mahalingam V, Moodley S, Truebody B, Mackenzie J, Steyn AJC, Perumal R, Berney M, Larsen MH, O'Donnell MR, Escuyer VE, Jacobs WR Jr. Rajagopalan S, et al. J Infect Dis. 2024 Oct 16:jiae438. doi: 10.1093/infdis/jiae438. Online ahead of print. J Infect Dis. 2024. PMID: 39412357
The PDIM paradox of Mycobacterium tuberculosis: new solutions to a persistent problem.
Mulholland CV, Wiggins TJ, Cui J, Vilchèze C, Rajagopalan S, Shultis MW, Reyes-Fernández EZ, Jacobs WR Jr, Berney M. Mulholland CV, et al. Among authors: rajagopalan s. bioRxiv [Preprint]. 2023 Oct 16:2023.10.16.562559. doi: 10.1101/2023.10.16.562559. bioRxiv. 2023. Update in: Nat Microbiol. 2024 Jun;9(6):1607-1618. doi: 10.1038/s41564-024-01697-8. PMID: 37905120 Free PMC article. Updated. Preprint.
Propionate prevents loss of the PDIM virulence lipid in Mycobacterium tuberculosis.
Mulholland CV, Wiggins TJ, Cui J, Vilchèze C, Rajagopalan S, Shultis MW, Reyes-Fernández EZ, Jacobs WR Jr, Berney M. Mulholland CV, et al. Among authors: rajagopalan s. Nat Microbiol. 2024 Jun;9(6):1607-1618. doi: 10.1038/s41564-024-01697-8. Epub 2024 May 13. Nat Microbiol. 2024. PMID: 38740932
MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues.
Feng M, Namanja-Magliano H, Rajagopalan S, Mishra T, Ducati RG, Hirsch BM, Kelly L, Szymczak W, Fajardo JE, Sidoli S, Fiser A, Jacobs WR, Schramm VL. Feng M, et al. Among authors: rajagopalan s. ACS Infect Dis. 2023 Apr 14;9(4):966-978. doi: 10.1021/acsinfecdis.2c00644. Epub 2023 Mar 15. ACS Infect Dis. 2023. PMID: 36920074 Free PMC article.
A recombinant herpes virus expressing influenza hemagglutinin confers protection and induces antibody-dependent cellular cytotoxicity.
Kaugars K, Dardick J, de Oliveira AP, Weiss KA, Lukose R, Kim J, Leung L, Rajagopalan S, Wolin S, Akabas L, Knipe DM, Bajic G, Jacobs WR Jr. Kaugars K, et al. Among authors: rajagopalan s. Proc Natl Acad Sci U S A. 2021 Aug 24;118(34):e2110714118. doi: 10.1073/pnas.2110714118. Proc Natl Acad Sci U S A. 2021. PMID: 34417304 Free PMC article.
1,333 results