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Page 1
LINE1 and PRC2 control nucleolar organization and repression of the 8C state in human ESCs.
Zhang J, Ataei L, Mittal K, Wu L, Caldwell L, Huynh L, Sarajideen S, Tse K, Simon MM, Mazid MA, Cook DP, Trcka D, Kwan T, Hoffman MM, Wrana JL, Esteban MA, Ramalho-Santos M. Zhang J, et al. Among authors: wrana jl. Dev Cell. 2024 Oct 14:S1534-5807(24)00574-4. doi: 10.1016/j.devcel.2024.09.024. Online ahead of print. Dev Cell. 2024. PMID: 39413784
Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells.
Kirk JS, Wang J, Long M, Rosario S, Tracz A, Ji Y, Kumar R, Liu X, Jamroze A, Singh PK, Puzanov I, Chatta G, Cheng Q, Huang J, Wrana JL, Lovell J, Yu H, Liu S, Shen MM, Liu T, Tang DG. Kirk JS, et al. Among authors: wrana jl. Cell Stem Cell. 2024 Aug 1;31(8):1203-1221.e7. doi: 10.1016/j.stem.2024.05.008. Epub 2024 Jun 14. Cell Stem Cell. 2024. PMID: 38878775
Early Inflammation and Interferon Signaling Direct Enhanced Intestinal Crypt Regeneration after Proton FLASH Radiotherapy.
Lim TL, Morral C, Verginadis II, Kim K, Luo L, Foley CJ, Kim MM, Li N, Yoshor B, Njah K, Putt M, Oliaei Motlagh SA, Velalopoulou A, Chowdhury P, Bicher S, Goia D, Lengner CJ, Wrana JL, Koumenis C, Minn AJ. Lim TL, et al. Among authors: wrana jl. bioRxiv [Preprint]. 2024 Aug 19:2024.08.16.608284. doi: 10.1101/2024.08.16.608284. bioRxiv. 2024. PMID: 39229237 Free PMC article. Preprint.
High-throughput sensitive screening of small molecule modulators of microexon alternative splicing using dual Nano and Firefly luciferase reporters.
Best AJ, Braunschweig U, Wu M, Farhangmehr S, Pasculescu A, Lim JJ, Comsa LC, Jen M, Wang J, Datti A, Wrana JL, Cordes SP, Al-Awar R, Han H, Blencowe BJ. Best AJ, et al. Among authors: wrana jl. Nat Commun. 2024 Jul 27;15(1):6328. doi: 10.1038/s41467-024-50399-6. Nat Commun. 2024. PMID: 39068192 Free PMC article.
p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.
Morral C, Ayyaz A, Kuo HC, Fink M, Verginadis II, Daniel AR, Burner DN, Driver LM, Satow S, Hasapis S, Ghinnagow R, Luo L, Ma Y, Attardi LD, Koumenis C, Minn AJ, Wrana JL, Lee CL, Kirsch DG. Morral C, et al. Among authors: wrana jl. Nat Commun. 2024 Apr 8;15(1):3018. doi: 10.1038/s41467-024-47124-8. Nat Commun. 2024. PMID: 38589357 Free PMC article.
p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.
Morral C, Ayyaz A, Kuo HC, Fink M, Verginadis I, Daniel AR, Burner DN, Driver LM, Satow S, Hasapis S, Ghinnagow R, Luo L, Ma Y, Attardi LD, Koumenis C, Minn AJ, Wrana JL, Lee CL, Kirsch DG. Morral C, et al. Among authors: wrana jl. bioRxiv [Preprint]. 2023 Apr 28:2023.04.27.538576. doi: 10.1101/2023.04.27.538576. bioRxiv. 2023. Update in: Nat Commun. 2024 Apr 8;15(1):3018. doi: 10.1038/s41467-024-47124-8. PMID: 37162959 Free PMC article. Updated. Preprint.
Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells.
Kirk JS, Wang J, Tracz A, Long M, Rosario SR, Ji Y, Kumar R, Liu X, Singh PK, Puzanov I, Chatta G, Cheng Q, Huang J, Wrana JL, Lovell J, Yu H, Liu S, Shen MM, Liu T, Tang DG. Kirk JS, et al. Among authors: wrana jl. bioRxiv [Preprint]. 2023 Mar 6:2023.03.03.530998. doi: 10.1101/2023.03.03.530998. bioRxiv. 2023. Update in: Cell Stem Cell. 2024 Aug 1;31(8):1203-1221.e7. doi: 10.1016/j.stem.2024.05.008. PMID: 36945493 Free PMC article. Updated. Preprint.
Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.
Langille E, Al-Zahrani KN, Ma Z, Liang M, Uuskula-Reimand L, Espin R, Teng K, Malik A, Bergholtz H, Ghamrasni SE, Afiuni-Zadeh S, Tsai R, Alvi S, Elia A, Lü Y, Oh RH, Kozma KJ, Trcka D, Narimatsu M, Liu JC, Nguyen T, Barutcu S, Loganathan SK, Bremner R, Bader GD, Egan SE, Cescon DW, Sørlie T, Wrana JL, Jackson HW, Wilson MD, Witkiewicz AK, Knudsen ES, Pujana MA, Wahl GM, Schramek D. Langille E, et al. Among authors: wrana jl. Cancer Discov. 2022 Dec 2;12(12):2930-2953. doi: 10.1158/2159-8290.CD-21-0865. Cancer Discov. 2022. PMID: 36108220 Free PMC article.
266 results