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Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners.
Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Sellick K, Spears E, Poffenberger G, Schornack AMR, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Coate KC, et al. Among authors: chen w. Mol Metab. 2024 Oct 20;90:102050. doi: 10.1016/j.molmet.2024.102050. Online ahead of print. Mol Metab. 2024. PMID: 39433176 Free article.
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners.
Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Spears E, Poffenberger G, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Coate KC, et al. Among authors: chen w. bioRxiv [Preprint]. 2024 Aug 7:2024.08.06.606926. doi: 10.1101/2024.08.06.606926. bioRxiv. 2024. Update in: Mol Metab. 2024 Oct 20;90:102050. doi: 10.1016/j.molmet.2024.102050. PMID: 39149351 Free PMC article. Updated. Preprint.
Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.
Dean ED, Li M, Prasad N, Wisniewski SN, Von Deylen A, Spaeth J, Maddison L, Botros A, Sedgeman LR, Bozadjieva N, Ilkayeva O, Coldren A, Poffenberger G, Shostak A, Semich MC, Aamodt KI, Phillips N, Yan H, Bernal-Mizrachi E, Corbin JD, Vickers KC, Levy SE, Dai C, Newgard C, Gu W, Stein R, Chen W, Powers AC. Dean ED, et al. Among authors: chen w. Cell Metab. 2017 Jun 6;25(6):1362-1373.e5. doi: 10.1016/j.cmet.2017.05.011. Cell Metab. 2017. PMID: 28591638 Free PMC article.
RIPK3-mediated inflammation is a conserved β cell response to ER stress.
Yang B, Maddison LA, Zaborska KE, Dai C, Yin L, Tang Z, Zang L, Jacobson DA, Powers AC, Chen W. Yang B, et al. Among authors: chen w. Sci Adv. 2020 Dec 18;6(51):eabd7272. doi: 10.1126/sciadv.abd7272. Print 2020 Dec. Sci Adv. 2020. PMID: 33355143 Free PMC article.
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