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ECM1 attenuates hepatic fibrosis by interfering with mediators of latent TGF-β1 activation.
Link F, Li Y, Zhao J, Munker S, Fan W, Nwosu ZC, Yao Y, Wang S, Huang C, Liebe R, Hammad S, Liu H, Shao C, Gao C, Sun B, Török NJ, Ding H, Ebert MP, Weng H, Ten Dijke P, Drasdo D, Dooley S, Wang S. Link F, et al. Among authors: drasdo d. Gut. 2024 Oct 24:gutjnl-2024-333213. doi: 10.1136/gutjnl-2024-333213. Online ahead of print. Gut. 2024. PMID: 39448254
A proof-of-concept pipeline to guide evaluation of tumor tissue perfusion by dynamic contrast-agent imaging: Direct simulation and inverse tracer-kinetic procedures.
Vignon-Clementel IE, Jagiella N, Dichamp J, Kowalski J, Lederle W, Laue H, Kiessling F, Sedlaczek O, Drasdo D. Vignon-Clementel IE, et al. Among authors: drasdo d. Front Bioinform. 2023 Apr 13;3:977228. doi: 10.3389/fbinf.2023.977228. eCollection 2023. Front Bioinform. 2023. PMID: 37122998 Free PMC article.
In vitro to in vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmacodynamic models and a multiscale spatial-temporal liver twin.
Dichamp J, Cellière G, Ghallab A, Hassan R, Boissier N, Hofmann U, Reinders J, Sezgin S, Zühlke S, Hengstler JG, Drasdo D. Dichamp J, et al. Among authors: drasdo d. Front Bioeng Biotechnol. 2023 Feb 2;11:1049564. doi: 10.3389/fbioe.2023.1049564. eCollection 2023. Front Bioeng Biotechnol. 2023. PMID: 36815881 Free PMC article.
Reply.
Vartak N, Elferink RO, van de Graaf S, Drasdo D, Hengstler J. Vartak N, et al. Among authors: drasdo d. Hepatology. 2022 Sep;76(3):E58. doi: 10.1002/hep.32485. Epub 2022 Apr 5. Hepatology. 2022. PMID: 35344603 No abstract available.
Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling.
Schneider KM, Candels LS, Hov JR, Myllys M, Hassan R, Schneider CV, Wahlström A, Mohs A, Zühlke S, Liao L, Elfers C, Kilic K, Henricsson M, Molinaro A, Hatting M, Zaza A, Drasdo D, Frissen M, Devlin AS, Gálvez EJC, Strowig T, Karlsen TH, Hengstler JG, Marschall HU, Ghallab A, Trautwein C. Schneider KM, et al. Among authors: drasdo d. Nat Metab. 2021 Sep;3(9):1228-1241. doi: 10.1038/s42255-021-00452-1. Epub 2021 Sep 22. Nat Metab. 2021. PMID: 34552267
63 results