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Severe COVID-19 Is Characterized by an Impaired Type I Interferon Response and Elevated Levels of Arginase Producing Granulocytic Myeloid Derived Suppressor Cells.
Dean MJ, Ochoa JB, Sanchez-Pino MD, Zabaleta J, Garai J, Del Valle L, Wyczechowska D, Baiamonte LB, Philbrook P, Majumder R, Vander Heide RS, Dunkenberger L, Thylur RP, Nossaman B, Roberts WM, Chapple AG, Wu J, Hicks C, Collins J, Luke B, Johnson R, Koul HK, Rees CA, Morris CR, Garcia-Diaz J, Ochoa AC. Dean MJ, et al. Among authors: wyczechowska d. Front Immunol. 2021 Jul 14;12:695972. doi: 10.3389/fimmu.2021.695972. eCollection 2021. Front Immunol. 2021. PMID: 34341659 Free PMC article.
Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer.
Ghonim MA, Ibba SV, Tarhuni AF, Errami Y, Luu HH, Dean MJ, El-Bahrawy AH, Wyczechowska D, Benslimane IA, Del Valle L, Al-Khami AA, Ochoa AC, Boulares AH. Ghonim MA, et al. Among authors: wyczechowska d. J Immunother Cancer. 2021 Jan;9(1):e001643. doi: 10.1136/jitc-2020-001643. J Immunother Cancer. 2021. PMID: 33495297 Free PMC article.
Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies.
Hossain F, Al-Khami AA, Wyczechowska D, Hernandez C, Zheng L, Reiss K, Valle LD, Trillo-Tinoco J, Maj T, Zou W, Rodriguez PC, Ochoa AC. Hossain F, et al. Among authors: wyczechowska d. Cancer Immunol Res. 2015 Nov;3(11):1236-47. doi: 10.1158/2326-6066.CIR-15-0036. Epub 2015 May 29. Cancer Immunol Res. 2015. PMID: 26025381 Free PMC article.
Fuelling the mechanisms of asthma: Increased fatty acid oxidation in inflammatory immune cells may represent a novel therapeutic target.
Al-Khami AA, Ghonim MA, Del Valle L, Ibba SV, Zheng L, Pyakurel K, Okpechi SC, Garay J, Wyczechowska D, Sanchez-Pino MD, Rodriguez PC, Boulares AH, Ochoa AC. Al-Khami AA, et al. Among authors: wyczechowska d. Clin Exp Allergy. 2017 Sep;47(9):1170-1184. doi: 10.1111/cea.12947. Epub 2017 Jul 5. Clin Exp Allergy. 2017. PMID: 28456994 Free PMC article.
PARP-1 Is Critical for Recruitment of Dendritic Cells to the Lung in a Mouse Model of Asthma but Dispensable for Their Differentiation and Function.
Echeverri Tirado LC, Ghonim MA, Wang J, Al-Khami AA, Wyczechowska D, Luu HH, Kim H, Sanchez-Pino MD, Yélamos J, Yassin LM, Boulares AH. Echeverri Tirado LC, et al. Among authors: wyczechowska d. Mediators Inflamm. 2019 Apr 24;2019:1656484. doi: 10.1155/2019/1656484. eCollection 2019. Mediators Inflamm. 2019. PMID: 31178661 Free PMC article.
Increased inflammatory low-density neutrophils in severe obesity and effect of bariatric surgery: Results from case-control and prospective cohort studies.
Sanchez-Pino MD, Richardson WS, Zabaleta J, Puttalingaiah RT, Chapple AG, Liu J, Kim Y, Ponder M, DeArmitt R, Baiamonte LB, Wyczechowska D, Zheng L, Al-Khami AA, Garai J, Martini R, Davis M, Gorham JK, Wooldridge JB, Rodriguez PC, Miele L, Ochoa AC. Sanchez-Pino MD, et al. Among authors: wyczechowska d. EBioMedicine. 2022 Mar;77:103910. doi: 10.1016/j.ebiom.2022.103910. Epub 2022 Mar 3. EBioMedicine. 2022. PMID: 35248994 Free PMC article.
Novel immunomodulatory properties of adenosine analogs promote their antiviral activity against SARS-CoV-2.
Monticone G, Huang Z, Hewins P, Cook T, Mirzalieva O, King B, Larter K, Miller-Ensminger T, Sanchez-Pino MD, Foster TP, Nichols OV, Ramsay AJ, Majumder S, Wyczechowska D, Tauzier D, Gravois E, Crabtree JS, Garai J, Li L, Zabaleta J, Barbier MT, Del Valle L, Jurado KA, Miele L. Monticone G, et al. Among authors: wyczechowska d. EMBO Rep. 2024 Aug;25(8):3547-3573. doi: 10.1038/s44319-024-00189-4. Epub 2024 Jul 15. EMBO Rep. 2024. PMID: 39009832 Free PMC article.
48 results