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Page 1
Discovery of BAY 2413555, First Selective Positive Allosteric Modulator of the M2 Receptor to Restore Cardiac Autonomic Balance.
Vakalopoulos A, Basting D, Brechmann M, Teller H, Boultadakis Arapinis M, Straub A, Mittendorf J, Meininghaus M, Müller T, Nowak-Reppel K, Schäfer M, Wittwer M, Kullmann M, Terjung C, Lang D, Poethko T, Marquardt T, Freudenberger T, Mondritzki T, Hüser J, Heckmann M, Tinel H. Vakalopoulos A, et al. Among authors: poethko t. J Med Chem. 2024 Nov 14;67(21):19165-19187. doi: 10.1021/acs.jmedchem.4c01590. Epub 2024 Oct 28. J Med Chem. 2024. PMID: 39463278
Preclinical in vitro and in vivo evaluation of [11C]ORM-13070 as PET ligand for alpha-2C adrenergic receptor occupancy using PET imaging in non-human primates.
Piel I, Constantinescu CC, de la Puente Bethencourt D, Bonsall DR, Rabiner EA, Zasadny KR, Llopis Amenta A, Wells LA, Poethko T, Prange W, Delbeck M. Piel I, et al. Among authors: poethko t. J Cereb Blood Flow Metab. 2024 Oct 31:271678X241291949. doi: 10.1177/0271678X241291949. Online ahead of print. J Cereb Blood Flow Metab. 2024. PMID: 39479946 Free PMC article.
Evaluation of alphavbeta3 integrin-targeted positron emission tomography tracer 18F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice.
Laitinen I, Saraste A, Weidl E, Poethko T, Weber AW, Nekolla SG, Leppänen P, Ylä-Herttuala S, Hölzlwimmer G, Walch A, Esposito I, Wester HJ, Knuuti J, Schwaiger M. Laitinen I, et al. Among authors: poethko t. Circ Cardiovasc Imaging. 2009 Jul;2(4):331-8. doi: 10.1161/CIRCIMAGING.108.846865. Epub 2009 May 13. Circ Cardiovasc Imaging. 2009. PMID: 19808614
Evaluation of a novel (18)F-labeled positron-emission tomography perfusion tracer for the assessment of myocardial infarct size in rats.
Sherif HM, Saraste A, Weidl E, Weber AW, Higuchi T, Reder S, Poethko T, Henriksen G, Casebier D, Robinson S, Wester HJ, Nekolla SG, Schwaiger M. Sherif HM, et al. Among authors: poethko t. Circ Cardiovasc Imaging. 2009 Mar;2(2):77-84. doi: 10.1161/CIRCIMAGING.108.815423. Epub 2009 Jan 26. Circ Cardiovasc Imaging. 2009. PMID: 19808572
Evaluation of the novel myocardial perfusion positron-emission tomography tracer 18F-BMS-747158-02: comparison to 13N-ammonia and validation with microspheres in a pig model.
Nekolla SG, Reder S, Saraste A, Higuchi T, Dzewas G, Preissel A, Huisman M, Poethko T, Schuster T, Yu M, Robinson S, Casebier D, Henke J, Wester HJ, Schwaiger M. Nekolla SG, et al. Among authors: poethko t. Circulation. 2009 May 5;119(17):2333-42. doi: 10.1161/CIRCULATIONAHA.108.797761. Epub 2009 Apr 20. Circulation. 2009. PMID: 19380625
Initial characterization of an 18F-labeled myocardial perfusion tracer.
Huisman MC, Higuchi T, Reder S, Nekolla SG, Poethko T, Wester HJ, Ziegler SI, Casebier DS, Robinson SP, Schwaiger M. Huisman MC, et al. Among authors: poethko t. J Nucl Med. 2008 Apr;49(4):630-6. doi: 10.2967/jnumed.107.044727. Epub 2008 Mar 14. J Nucl Med. 2008. PMID: 18344426 Free article.
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