Hoffman RM - Search Results

1

Extensive DNA Damage and Loss of Cell Viability Occur Synergistically With the Combination of Recombinant Methioninase and Paclitaxel on Pancreatic Cancer Cells which Report DNA-Damage Response in Real Time.

Morinaga S, Han Q, Mizuta K, Kang BM, Sato M, Bouvet M, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Higuchi T, Tsuchiya H, Demura S, Hoffman RM. Morinaga S, et al. Among authors: hoffman rm. Cancer Genomics Proteomics. 2024 Nov-Dec;21(6):585-590. doi: 10.21873/cgp.20475. Cancer Genomics Proteomics. 2024. PMID: 39467627 Free PMC article.

2

Depletion of serum methionine by methioninase in mice.

Lishko VK, Lishko OV, Hoffman RM. Lishko VK, et al. Among authors: hoffman rm. Anticancer Res. 1993 Sep-Oct;13(5A):1465-8. Anticancer Res. 1993. PMID: 8239522

3

Anticancer efficacy of methioninase in vivo.

Tan Y, Xu M, Guo H, Sun X, Kubota T, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Anticancer Res. 1996 Nov-Dec;16(6C):3931-6. Anticancer Res. 1996. PMID: 9042315

4

Serum methionine depletion without side effects by methioninase in metastatic breast cancer patients.

Tan Y, Zavala J Sr, Xu M, Zavala J Jr, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Anticancer Res. 1996 Nov-Dec;16(6C):3937-42. Anticancer Res. 1996. PMID: 9042316 Clinical Trial.

5

Methioninase: a therapeutic for diseases related to altered methionine metabolism and transmethylation: cancer, heart disease, obesity, aging, and Parkinson's disease.

Hoffman RM. Hoffman RM. Hum Cell. 1997 Mar;10(1):69-80. Hum Cell. 1997. PMID: 9234067 Review.

6

Recombinant methioninase infusion reduces the biochemical endpoint of serum methionine with minimal toxicity in high-stage cancer patients.

Tan Y, Zavala J Sr, Han Q, Xu M, Sun X, Tan X, Tan X, Magana R, Geller J, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Anticancer Res. 1997 Sep-Oct;17(5B):3857-60. Anticancer Res. 1997. PMID: 9427792 Clinical Trial.

7

Polyethylene glycol conjugation of recombinant methioninase for cancer therapy.

Tan Y, Sun X, Xu M, An Z, Tan X, Han Q, Miljkovic DA, Yang M, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Protein Expr Purif. 1998 Feb;12(1):45-52. doi: 10.1006/prep.1997.0805. Protein Expr Purif. 1998. PMID: 9473456

8

Anticancer efficacy in vivo and in vitro, synergy with 5-fluorouracil, and safety of recombinant methioninase.

Yoshioka T, Wada T, Uchida N, Maki H, Yoshida H, Ide N, Kasai H, Hojo K, Shono K, Maekawa R, Yagi S, Hoffman RM, Sugita K. Yoshioka T, et al. Among authors: hoffman rm. Cancer Res. 1998 Jun 15;58(12):2583-7. Cancer Res. 1998. PMID: 9635582

9

High expression, purification, and properties of recombinant homocysteine alpha, gamma-lyase.

Han Q, Lenz M, Tan Y, Xu M, Sun X, Tan X, Tan X, Tang L, Miljkovic D, Hoffman RM. Han Q, et al. Among authors: hoffman rm. Protein Expr Purif. 1998 Nov;14(2):267-74. doi: 10.1006/prep.1998.0955. Protein Expr Purif. 1998. PMID: 9790890

10

Efficacy of recombinant methioninase in combination with cisplatin on human colon tumors in nude mice.

Tan Y, Sun X, Xu M, Tan X, Sasson A, Rashidi B, Han Q, Tan X, Wang X, An Z, Sun FX, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Clin Cancer Res. 1999 Aug;5(8):2157-63. Clin Cancer Res. 1999. PMID: 10473100

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