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Surviving septic patients endotyped with a functional assay demonstrate active immune responses.
Price AD, Becker ER, Barrios EL, Mazer MB, McGonagill PW, Bergmann CB, Goodman MD, Gould RW, Rao M, Polcz VE, Kucaba TA, Walton AH, Miles S, Xu J, Liang M, Loftus TJ, Efron PA, Remy KE, Brakenridge SC, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Price AD, et al. Among authors: caldwell cc. Front Immunol. 2024 Oct 14;15:1418613. doi: 10.3389/fimmu.2024.1418613. eCollection 2024. Front Immunol. 2024. PMID: 39469706 Free PMC article.
Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpot.
Barrios EL, Mazer MB, McGonagill PW, Bergmann CB, Goodman MD, Gould RW, Rao M, Polcz VE, Davis RJ, Del Toro DE, Dirain ML, Dram A, Hale LO, Heidarian M, Kim CY, Kucaba TA, Lanz JP, McCray AE, Meszaros S, Miles S, Nelson CR, Rocha IL, Silva EE, Ungaro RF, Walton AH, Xu J, Zeumer-Spataro L, Drewry AM, Liang M, Bible LE, Loftus TJ, Turnbull IR, Efron PA, Remy KE, Brakenridge SC, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Barrios EL, et al. Among authors: caldwell cc. JCI Insight. 2024 Jan 23;9(2):e175785. doi: 10.1172/jci.insight.175785. JCI Insight. 2024. PMID: 38100268 Free PMC article.
Development and optimization of a diluted whole blood ELISpot assay to test immune function.
Ungaro RF, Xu J, Kucaba TA, Rao M, Bergmann CB, Brakenridge SC, Efron PA, Goodman MD, Gould RW, Hotchkiss RS, Liang M, Mazer MB, McGonagill PW, Moldawer LL, Remy KE, Turnbull IR, Caldwell CC, Badovinac VP, Griffith TS. Ungaro RF, et al. Among authors: caldwell cc. J Immunol Methods. 2024 Oct;533:113743. doi: 10.1016/j.jim.2024.113743. Epub 2024 Aug 13. J Immunol Methods. 2024. PMID: 39147231 Free article.
TEMPORAL CHANGES IN INNATE AND ADAPTIVE IMMUNITY DURING SEPSIS AS DETERMINED BY ELISPOT.
Unsinger J, Osborne D, Walton AH, Han E, Sheets L, Mazer MB, Remy KE, Griffith TS, Rao M, Badovinac VP, Brakenridge SC, Turnbull I, Efron PA, Moldawer LL, Caldwell CC, Hotchkiss RS. Unsinger J, et al. Among authors: caldwell cc. Shock. 2024 Aug 1;62(2):255-264. doi: 10.1097/SHK.0000000000002377. Epub 2024 May 3. Shock. 2024. PMID: 38754032
Temporal Changes in Innate and Adaptive Immunity During Sepsis as Determined by ELISpot.
Unsinger J, Osborne D, Walton AH, Han E, Sheets L, Mazer MB, Remy KE, Griffith TS, Rao M, Badovinac VP, Brackenridge SC, Turnbull I, Efron PA, Moldawer LL, Caldwell CC, Hotchkiss RS. Unsinger J, et al. Among authors: caldwell cc. bioRxiv [Preprint]. 2023 Dec 14:2023.12.14.571668. doi: 10.1101/2023.12.14.571668. bioRxiv. 2023. Update in: Shock. 2024 Aug 1;62(2):255-264. doi: 10.1097/SHK.0000000000002377. PMID: 38168302 Free PMC article. Updated. Preprint.
Adverse Long-Term Outcomes and an Immune Suppressed Endotype in Sepsis Patients with Reduced Interferon-γELISpot: A Multicenter, Prospective Observational Study.
Barrios EA, Mazer MB, McGonagill P, Bergmann CB, Goodman MD, Gould R, Rao M, Polcz V, Davis R, Del Toro D, Dirain M, Dram A, Hale L, Heidarian M, Kucaba TA, Lanz JP, McCray A, Meszaros S, Miles S, Nelson C, Rocha I, Silva EE, Ungaro R, Walton A, Xu J, Zeumer-Spataro L, Drewry A, Liang M, Bible LE, Loftus T, Turnbull I, Efron PA, Remy KE, Brakenridge S, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Barrios EA, et al. Among authors: caldwell cc. medRxiv [Preprint]. 2023 Sep 24:2023.09.13.23295360. doi: 10.1101/2023.09.13.23295360. medRxiv. 2023. Update in: JCI Insight. 2024 Jan 23;9(2):e175785. doi: 10.1172/jci.insight.175785. PMID: 37745385 Free PMC article. Updated. Preprint.
156 results