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Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis.
Cai Z, Li CF, Han F, Liu C, Zhang A, Hsu CC, Peng D, Zhang X, Jin G, Rezaeian AH, Wang G, Zhang W, Pan BS, Wang CY, Wang YH, Wu SY, Yang SC, Hsu FC, D'Agostino RB Jr, Furdui CM, Kucera GL, Parks JS, Chilton FH, Huang CY, Tsai FJ, Pasche B, Watabe K, Lin HK. Cai Z, et al. Among authors: zhang a, zhang w, zhang x. Mol Cell. 2020 Oct 15;80(2):263-278.e7. doi: 10.1016/j.molcel.2020.09.018. Epub 2020 Oct 5. Mol Cell. 2020. PMID: 33022274 Free PMC article.
Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK.
Hsu CC, Zhang X, Wang G, Zhang W, Cai Z, Pan BS, Gu H, Xu C, Jin G, Xu X, Manne RK, Jin Y, Yan W, Shao J, Chen T, Lin E, Ketkar A, Eoff R, Xu ZG, Chen ZZ, Li HY, Lin HK. Hsu CC, et al. Among authors: zhang w, zhang x. Mol Cell. 2021 Sep 16;81(18):3803-3819.e7. doi: 10.1016/j.molcel.2021.08.025. Mol Cell. 2021. PMID: 34547240 Free PMC article.
SIRPγ-expressing cancer stem-like cells promote immune escape of lung cancer via Hippo signaling.
Xu C, Jin G, Wu H, Cui W, Wang YH, Manne RK, Wang G, Zhang W, Zhang X, Han F, Cai Z, Pan BS, Hsu CC, Liu Y, Zhang A, Long J, Zou H, Wang S, Ma X, Duan J, Wang B, Liu W, Lan H, Xiong Q, Xue G, Chen Z, Xu Z, Furth ME, Haigh Molina S, Lu Y, Xie D, Bian XW, Lin HK. Xu C, et al. Among authors: zhang a, zhang w, zhang x. J Clin Invest. 2022 Mar 1;132(5):e141797. doi: 10.1172/JCI141797. J Clin Invest. 2022. PMID: 35229723 Free PMC article.
TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression.
Zhang X, Li CF, Zhang L, Wu CY, Han L, Jin G, Rezaeian AH, Han F, Liu C, Xu C, Xu X, Huang CY, Tsai FJ, Tsai CH, Watabe K, Lin HK. Zhang X, et al. Among authors: zhang l. Mol Cell. 2016 Nov 17;64(4):803-814. doi: 10.1016/j.molcel.2016.10.002. Epub 2016 Nov 3. Mol Cell. 2016. PMID: 27818144 Free PMC article.
H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis.
Zhang X, Li B, Rezaeian AH, Xu X, Chou PC, Jin G, Han F, Pan BS, Wang CY, Long J, Zhang A, Huang CY, Tsai FJ, Tsai CH, Logothetis C, Lin HK. Zhang X, et al. Among authors: zhang a. Nat Commun. 2017 Mar 16;8:14799. doi: 10.1038/ncomms14799. Nat Commun. 2017. PMID: 28300060 Free PMC article.
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