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Promoting readthrough of nonsense mutations in CF mouse model: Biodistribution and efficacy of NV848 in rescuing CFTR protein expression.
Mol Ther. 2024 Oct 28:S1525-0016(24)00688-9. doi: 10.1016/j.ymthe.2024.10.028. Online ahead of print.
Mol Ther. 2024.
PMID: 39473179
Free article.
Readthrough Approach Using NV Translational Readthrough-Inducing Drugs (TRIDs): A Study of the Possible Off-Target Effects on Natural Termination Codons (NTCs) on TP53 and Housekeeping Gene Expression.
Perriera R, Vitale E, Pibiri I, Carollo PS, Ricci D, Corrao F, Fiduccia I, Melfi R, Zizzo MG, Tutone M, Pace A, Lentini L.
Perriera R, et al. Among authors: fiduccia i.
Int J Mol Sci. 2023 Oct 11;24(20):15084. doi: 10.3390/ijms242015084.
Int J Mol Sci. 2023.
PMID: 37894764
Free PMC article.
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Investigating the Inhibition of FTSJ1, a Tryptophan tRNA-Specific 2'-O-Methyltransferase by NV TRIDs, as a Mechanism of Readthrough in Nonsense Mutated CFTR.
Carollo PS, Tutone M, Culletta G, Fiduccia I, Corrao F, Pibiri I, Di Leonardo A, Zizzo MG, Melfi R, Pace A, Almerico AM, Lentini L.
Carollo PS, et al. Among authors: fiduccia i.
Int J Mol Sci. 2023 Jun 1;24(11):9609. doi: 10.3390/ijms24119609.
Int J Mol Sci. 2023.
PMID: 37298560
Free PMC article.
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Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation.
Corrao F, Zizzo MG, Tutone M, Melfi R, Fiduccia I, Carollo PS, Leonardo AD, Caldara G, Perriera R, Pace A, Belmonte B, Sammataro S, Pibiri I, Lentini L.
Corrao F, et al. Among authors: fiduccia i.
Biomed Pharmacother. 2022 Dec;156:113886. doi: 10.1016/j.biopha.2022.113886. Epub 2022 Oct 18.
Biomed Pharmacother. 2022.
PMID: 36265311
Free article.
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