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Page 1
Liposomal formulation with thiazolic compounds against bacterial efflux pumps.
de Almeida RS, Freitas PR, Justino de Araujo AC, Tintino SR, Ribeiro-Filho J, Miranda GM, Sigueira GM, Gonçalves SA, Carvalho DT, de Souza TB, Santos Folquitto LRD, Dias DF, Raposo A, Saraiva A, Han H, Coutinho HDM. de Almeida RS, et al. Among authors: freitas pr. Biomed Pharmacother. 2024 Oct 29;180:117600. doi: 10.1016/j.biopha.2024.117600. Online ahead of print. Biomed Pharmacother. 2024. PMID: 39476763
Assessment In vitro and In silico of the Activity of Thiadiazines as NorA Efflux Pump Inhibitors.
de Araújo ACJ, Freitas PR, Araújo IM, de Oliveira Borges JA, Gonçalves SA, Paulo CLR, Almeida RS, de Moraes Oliveira-Tintino CD, de Araújo-Neto JB, Dos Santos Nascimento IJ, de Araújo-Júnior JX, da Silva-Júnior EF, de Aquino TM, Junior FJBM, Marinho ES, Dos Santos HS, de Alencar Menezes IR, Tintino SR, Coutinho HDM, Braga MFBM. de Araújo ACJ, et al. Among authors: freitas pr. Curr Microbiol. 2024 Aug 24;81(10):325. doi: 10.1007/s00284-024-03836-0. Curr Microbiol. 2024. PMID: 39182011
Thiazine-derived compounds in inhibiting efflux pump in Staphylococcus aureus K2068, mepA gene expression, and membrane permeability alteration.
Freitas PR, de Araújo ACJ, Araújo IM, de Almeida RS, Borges JAO, Paulo CLR, Oliveira-Tintino CDM, Miranda GM, Araújo-Neto JB, Nascimento IJS, Araújo-Júnior JX, Silva JMA, Balbino TCL, Silva-Júnior EF, Aquino TM, Mendonca-Junior FJB, Marinho ES, Santos HS, Lima CMG, Obaidullah AJ, Bin Emran T, Cunha FAB, Menezes IRA, Tintino SR, Coutinho HDM. Freitas PR, et al. Biomed Pharmacother. 2024 Oct;179:117291. doi: 10.1016/j.biopha.2024.117291. Epub 2024 Aug 14. Biomed Pharmacother. 2024. PMID: 39146766 Free article.
Chemical composition and antibacterial effects of Etlingera elatior (Jack) R.M. Smith against Staphylococcus aureus efflux pumps.
de Sousa Ferreira F, de Araújo Neto JB, de Morais Oliveira-Tintino CD, de Araújo ACJ, Ribeiro-Filho J, Freitas PR, Araújo IM, Lima MA, de Azevedo FR, Tintino SR, Coutinho HDM, Navarro DMDAF. de Sousa Ferreira F, et al. Among authors: freitas pr. Chem Biol Interact. 2023 Dec 1;386:110751. doi: 10.1016/j.cbi.2023.110751. Epub 2023 Oct 10. Chem Biol Interact. 2023. PMID: 37821044
Potentiating-antibiotic activity and absorption, distribution, metabolism, excretion and toxicity properties (ADMET) analysis of synthetic thiadiazines against multi-drug resistant (MDR) strains.
de Araújo ACJ, Freitas PR, Araújo IM, Siqueira GM, de Oliveira Borges JA, Alves DS, Miranda GM, Dos Santos Nascimento IJ, de Araújo-Júnior JX, da Silva-Júnior EF, de Aquino TM, Junior FJBM, Marinho ES, Dos Santos HS, Tintino SR, Coutinho HDM. de Araújo ACJ, et al. Among authors: freitas pr. Fundam Clin Pharmacol. 2024 Feb;38(1):84-98. doi: 10.1111/fcp.12950. Epub 2023 Aug 30. Fundam Clin Pharmacol. 2024. PMID: 37649138
Synthesis, spectroscopic characterization, and antibacterial activity of chalcone (2E)-1-(3'-aminophenyl)-3-(4-dimethylaminophenyl)-prop-2-en-1-one against multiresistant Staphylococcus aureus carrier of efflux pump mechanisms and β-lactamase.
da Silva L, Donato IA, Bezerra SR, Dos Santos HS, Bandeira PN, do Nascimento MTR, Guedes JM, Freitas PR, de Araújo ACJ, de Freitas TS, Coutinho HDM, de Matos YMLS, de Oliveira LCC, da Cunha FAB. da Silva L, et al. Among authors: freitas pr. Fundam Clin Pharmacol. 2024 Feb;38(1):60-71. doi: 10.1111/fcp.12938. Epub 2023 Jul 27. Fundam Clin Pharmacol. 2024. PMID: 37497790
Antibiotic-Potentiating Activity of the Schinus terebinthifolius Raddi Essential Oil against MDR Bacterial Strains.
Costa da Silva MM, Bezerra de Araújo Neto J, Lucas Dos Santos AT, de Morais Oliveira-Tintino CD, de Araújo ACJ, Freitas PR, da Silva LE, do Amaral W, Deschamps C, de Azevedo FR, Gonçalves Lima CM, Golubkina N, Calixto-Júnior JT, Ribeiro-Filho J, Coutinho HDM, Caruso G, Tintino SR. Costa da Silva MM, et al. Among authors: freitas pr. Plants (Basel). 2023 Apr 8;12(8):1587. doi: 10.3390/plants12081587. Plants (Basel). 2023. PMID: 37111810 Free PMC article.
Dioclea violacea lectin increases the effect of neomycin against multidrug-resistant strains and promotes the purification of the antibiotic in immobilized lectin column.
Santos MHC, Santos VF, Freitas PR, Silva RRS, Roma RR, Santos ALE, Ribeiro DA, Coutinho HDM, Rocha BAM, Oliveira MME, Teixeira CS. Santos MHC, et al. Among authors: freitas pr. Int J Biol Macromol. 2023 May 1;236:123941. doi: 10.1016/j.ijbiomac.2023.123941. Epub 2023 Mar 7. Int J Biol Macromol. 2023. PMID: 36893486
Terpenes as bacterial efflux pump inhibitors: A systematic review.
Dias KJSO, Miranda GM, Bessa JR, Araújo ACJ, Freitas PR, Almeida RS, Paulo CLR, Neto JBA, Coutinho HDM, Ribeiro-Filho J. Dias KJSO, et al. Among authors: freitas pr. Front Pharmacol. 2022 Oct 13;13:953982. doi: 10.3389/fphar.2022.953982. eCollection 2022. Front Pharmacol. 2022. PMID: 36313340 Free PMC article.
Dihydroeugenol derivatives associated with blue LED light: A different form to face multidrug resistant (MDR) bacteria.
de Sousa AK, Rocha JE, de Freitas TS, Freitas PR, Pereira RLS, Leandro MKDNS, Machado JVC, de Oliveira LM, Torres Sierra EJ, Pereira Júnior FN, Carvalho DT, Coutinho HDM, Quintans Júnior LJ. de Sousa AK, et al. Among authors: freitas pr. Microb Pathog. 2022 Dec;173(Pt A):105827. doi: 10.1016/j.micpath.2022.105827. Epub 2022 Oct 13. Microb Pathog. 2022. PMID: 36243385
34 results