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Mitochondrial-targeted plastoquinone therapy ameliorates early onset muscle weakness that precedes ovarian cancer cachexia in mice.
Delfinis LJ, Khajehzadehshoushtar S, Flewwelling LD, Andrews NJ, Garibotti MC, Gandhi S, Brahmbhatt AN, Morris BA, Garlisi B, Lauks S, Aitken C, Tsitkanou S, Simpson JA, Greene NP, Cheng AJ, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: greene np. bioRxiv [Preprint]. 2024 Oct 25:2024.10.22.619751. doi: 10.1101/2024.10.22.619751. bioRxiv. 2024. PMID: 39484418 Free PMC article. Preprint.
The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates MYC as a Hypertrophic Regulator That is Sufficient for Growth.
Edman S, Jones RG 3rd, Jannig PR, Fernandez-Gonzalo R, Norrbom J, Thomas NT, Khadgi S, Koopmans PJ, Morena F, Peterson CS, Scott LN, Greene NP, Figueiredo VC, Fry CS, Zhengye L, Lanner JT, Wen Y, Alkner B, Murach KA, von Walden F. Edman S, et al. Among authors: greene np. bioRxiv [Preprint]. 2024 Mar 27:2024.03.26.586857. doi: 10.1101/2024.03.26.586857. bioRxiv. 2024. PMID: 38586026 Free PMC article. Preprint.
The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth.
Edman S, Jones Iii RG, Jannig PR, Fernandez-Gonzalo R, Norrbom J, Thomas NT, Khadgi S, Koopmans PJ, Morena F, Chambers TL, Peterson CS, Scott LN, Greene NP, Figueiredo VC, Fry CS, Zhengye L, Lanner JT, Wen Y, Alkner B, Murach KA, von Walden F. Edman S, et al. Among authors: greene np. EMBO Rep. 2024 Oct 31. doi: 10.1038/s44319-024-00299-z. Online ahead of print. EMBO Rep. 2024. PMID: 39482487 Free article.
Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice.
Tsitkanou S, Morena da Silva F, Cabrera AR, Schrems ER, Muhyudin R, Koopmans PJ, Khadgi S, Lim S, Delfinis LJ, Washington TA, Murach KA, Perry CGR, Greene NP. Tsitkanou S, et al. Among authors: greene np. Am J Physiol Cell Physiol. 2024 Nov 1;327(5):C1308-C1322. doi: 10.1152/ajpcell.00497.2024. Epub 2024 Sep 30. Am J Physiol Cell Physiol. 2024. PMID: 39344417
Muscle weakness and mitochondrial stress occur before severe metastasis in a novel mouse model of ovarian cancer cachexia.
Delfinis LJ, Ogilvie LM, Khajehzadehshoushtar S, Gandhi S, Garibotti MC, Thuhan AK, Matuszewska K, Pereira M, Jones RG 3rd, Cheng AJ, Hawke TJ, Greene NP, Murach KA, Simpson JA, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: greene np. Mol Metab. 2024 Aug;86:101976. doi: 10.1016/j.molmet.2024.101976. Epub 2024 Jun 24. Mol Metab. 2024. PMID: 38925248 Free PMC article.
Muscle weakness and mitochondrial stress occur before metastasis in a novel mouse model of ovarian cancer cachexia.
Delfinis LJ, Ogilvie LM, Khajehzadehshoushtar S, Gandhi S, Garibotti MC, Thuhan AK, Matuszewska K, Pereira M, Jones RG 3rd, Cheng AJ, Hawke TJ, Greene NP, Murach KA, Simpson JA, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: greene np. bioRxiv [Preprint]. 2024 Apr 8:2024.04.08.588639. doi: 10.1101/2024.04.08.588639. bioRxiv. 2024. Update in: Mol Metab. 2024 Aug;86:101976. doi: 10.1016/j.molmet.2024.101976. PMID: 38645227 Free PMC article. Updated. Preprint.
90 results