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Page 1
mRNA vaccine-induced IgG mediates nasal SARS-CoV-2 clearance in mice.
Fricke C, Ulrich L, Kochmann J, Gergen J, Kovacikova K, Roth N, Beer J, Schnepf D, Mettenleiter TC, Rauch S, Petsch B, Hoffmann D, Beer M, Corleis B, Dorhoi A. Fricke C, et al. Among authors: schnepf d. Mol Ther Nucleic Acids. 2024 Oct 15;35(4):102360. doi: 10.1016/j.omtn.2024.102360. eCollection 2024 Dec 10. Mol Ther Nucleic Acids. 2024. PMID: 39524696 Free PMC article.
Sustained innate interferon is an essential inducer of tertiary lymphoid structures.
Calvanese AL, Cecconi V, Stäheli S, Schnepf D, Nater M, Pereira P, Gschwend J, Heikenwälder M, Schneider C, Ludewig B, Silina K, van den Broek M. Calvanese AL, et al. Among authors: schnepf d. Eur J Immunol. 2024 Oct;54(10):e2451207. doi: 10.1002/eji.202451207. Epub 2024 Jul 9. Eur J Immunol. 2024. PMID: 38980268
Necroptosis blockade prevents lung injury in severe influenza.
Gautam A, Boyd DF, Nikhar S, Zhang T, Siokas I, Van de Velde LA, Gaevert J, Meliopoulos V, Thapa B, Rodriguez DA, Cai KQ, Yin C, Schnepf D, Beer J, DeAntoneo C, Williams RM, Shubina M, Livingston B, Zhang D, Andrake MD, Lee S, Boda R, Duddupudi AL, Crawford JC, Vogel P, Loch C, Schwemmle M, Fritz LC, Schultz-Cherry S, Green DR, Cuny GD, Thomas PG, Degterev A, Balachandran S. Gautam A, et al. Among authors: schnepf d. Nature. 2024 Apr;628(8009):835-843. doi: 10.1038/s41586-024-07265-8. Epub 2024 Apr 10. Nature. 2024. PMID: 38600381
mRNA 3'UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus.
Bergant V, Schnepf D, de Andrade Krätzig N, Hubel P, Urban C, Engleitner T, Dijkman R, Ryffel B, Steiger K, Knolle PA, Kochs G, Rad R, Staeheli P, Pichlmair A. Bergant V, et al. Among authors: schnepf d. Nat Commun. 2023 Aug 15;14(1):4906. doi: 10.1038/s41467-023-40469-6. Nat Commun. 2023. PMID: 37582777 Free PMC article.
Total escape of SARS-CoV-2 from dual monoclonal antibody therapy in an immunocompromised patient.
Jaki L, Weigang S, Kern L, Kramme S, Wrobel AG, Grawitz AB, Nawrath P, Martin SR, Dähne T, Beer J, Disch M, Kolb P, Gutbrod L, Reuter S, Warnatz K, Schwemmle M, Gamblin SJ, Neumann-Haefelin E, Schnepf D, Welte T, Kochs G, Huzly D, Panning M, Fuchs J. Jaki L, et al. Among authors: schnepf d. Nat Commun. 2023 Apr 10;14(1):1999. doi: 10.1038/s41467-023-37591-w. Nat Commun. 2023. PMID: 37037847 Free PMC article.
IFN-λ is protective against lethal oral Toxoplasma gondii infection.
Murillo-León M, Bastidas-Quintero AM, Endres NS, Schnepf D, Delgado-Betancourt E, Ohnemus A, Taylor GA, Schwemmle M, Staeheli P, Steinfeldt T. Murillo-León M, et al. Among authors: schnepf d. bioRxiv [Preprint]. 2023 Feb 24:2023.02.24.529861. doi: 10.1101/2023.02.24.529861. bioRxiv. 2023. PMID: 36865100 Free PMC article. Preprint.
Impaired immune response drives age-dependent severity of COVID-19.
Beer J, Crotta S, Breithaupt A, Ohnemus A, Becker J, Sachs B, Kern L, Llorian M, Ebert N, Labroussaa F, Nhu Thao TT, Trueeb BS, Jores J, Thiel V, Beer M, Fuchs J, Kochs G, Wack A, Schwemmle M, Schnepf D. Beer J, et al. Among authors: schnepf d. J Exp Med. 2022 Dec 5;219(12):e20220621. doi: 10.1084/jem.20220621. Epub 2022 Sep 21. J Exp Med. 2022. PMID: 36129445 Free PMC article.
Antibody escape and global spread of SARS-CoV-2 lineage A.27.
Kaleta T, Kern L, Hong SL, Hölzer M, Kochs G, Beer J, Schnepf D, Schwemmle M, Bollen N, Kolb P, Huber M, Ulferts S, Weigang S, Dudas G, Wittig A, Jaki L, Padane A, Lagare A, Salou M, Ozer EA, Nnaemeka N, Odoom JK, Rutayisire R, Benkahla A, Akoua-Koffi C, Ouedraogo AS, Simon-Lorière E, Enouf V, Kröger S, Calvignac-Spencer S, Baele G, Panning M, Fuchs J. Kaleta T, et al. Among authors: schnepf d. Nat Commun. 2022 Mar 3;13(1):1152. doi: 10.1038/s41467-022-28766-y. Nat Commun. 2022. PMID: 35241661 Free PMC article.
Biparatopic nanobodies protect mice from lethal challenge with SARS-CoV-2 variants of concern.
Wagner TR, Schnepf D, Beer J, Ruetalo N, Klingel K, Kaiser PD, Junker D, Sauter M, Traenkle B, Frecot DI, Becker M, Schneiderhan-Marra N, Ohnemus A, Schwemmle M, Schindler M, Rothbauer U. Wagner TR, et al. Among authors: schnepf d. EMBO Rep. 2022 Feb 3;23(2):e53865. doi: 10.15252/embr.202153865. Epub 2021 Dec 20. EMBO Rep. 2022. PMID: 34927793 Free PMC article.
Microbiota-dependent increase in δ-valerobetaine alters neuronal function and is responsible for age-related cognitive decline.
Mossad O, Nent E, Woltemate S, Folschweiller S, Buescher JM, Schnepf D, Erny D, Staeheli P, Bartos M, Szalay A, Stecher B, Vital M, Sauer JF, Lämmermann T, Prinz M, Blank T. Mossad O, et al. Among authors: schnepf d. Nat Aging. 2021 Dec;1(12):1127-1136. doi: 10.1038/s43587-021-00141-4. Epub 2021 Dec 20. Nat Aging. 2021. PMID: 37117525
25 results