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Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia.
Voit RA, Liao X, Caulier A, Antoszewski M, Cohen B, Armant M, Lu HY, Fleming TJ, Kamal E, Wahlster L, Roche AM, Everett JK, Petrichenko A, Huang MM, Clarke W, Myers KC, Forester C, Perez-Atayde A, Bushman FD, Pellin D, Shimamura A, Williams DA, Sankaran VG. Voit RA, et al. Among authors: wahlster l. Cell Stem Cell. 2024 Nov 8:S1934-5909(24)00374-6. doi: 10.1016/j.stem.2024.10.012. Online ahead of print. Cell Stem Cell. 2024. PMID: 39532107
A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children.
de Smith AJ, Wahlster L, Jeon S, Kachuri L, Black S, Langie J, Cato LD, Nakatsuka N, Chan TF, Xia G, Mazumder S, Yang W, Gazal S, Eng C, Hu D, Burchard EG, Ziv E, Metayer C, Mancuso N, Yang JJ, Ma X, Wiemels JL, Yu F, Chiang CWK, Sankaran VG. de Smith AJ, et al. Among authors: wahlster l. Cell Genom. 2024 Apr 10;4(4):100526. doi: 10.1016/j.xgen.2024.100526. Epub 2024 Mar 26. Cell Genom. 2024. PMID: 38537633 Free PMC article.
Deciphering cell states and genealogies of human haematopoiesis.
Weng C, Yu F, Yang D, Poeschla M, Liggett LA, Jones MG, Qiu X, Wahlster L, Caulier A, Hussmann JA, Schnell A, Yost KE, Koblan LW, Martin-Rufino JD, Min J, Hammond A, Ssozi D, Bueno R, Mallidi H, Kreso A, Escabi J, Rideout WM 3rd, Jacks T, Hormoz S, van Galen P, Weissman JS, Sankaran VG. Weng C, et al. Among authors: wahlster l. Nature. 2024 Mar;627(8003):389-398. doi: 10.1038/s41586-024-07066-z. Epub 2024 Jan 22. Nature. 2024. PMID: 38253266 Free PMC article.
High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia.
Saffari A, Brechmann B, Böger C, Saber WA, Jumo H, Whye D, Wood D, Wahlster L, Alecu JE, Ziegler M, Scheffold M, Winden K, Hubbs J, Buttermore ED, Barrett L, Borner GHH, Davies AK, Ebrahimi-Fakhari D, Sahin M. Saffari A, et al. Among authors: wahlster l. Nat Commun. 2024 Jan 17;15(1):584. doi: 10.1038/s41467-023-44264-1. Nat Commun. 2024. PMID: 38233389 Free PMC article.
High-Content Small Molecule Screen Identifies a Novel Compound That Restores AP-4-Dependent Protein Trafficking in Neuronal Models of AP-4-Associated Hereditary Spastic Paraplegia.
Saffari A, Brechmann B, Boeger C, Saber WA, Jumo H, Whye D, Wood D, Wahlster L, Alecu J, Ziegler M, Scheffold M, Winden K, Hubbs J, Buttermore E, Barrett L, Borner G, Davies A, Sahin M, Ebrahimi-Fakhari D. Saffari A, et al. Among authors: wahlster l. Res Sq [Preprint]. 2023 Jun 12:rs.3.rs-3036166. doi: 10.21203/rs.3.rs-3036166/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Jan 17;15(1):584. doi: 10.1038/s41467-023-44264-1. PMID: 37398196 Free PMC article. Updated. Preprint.
Massively parallel base editing to map variant effects in human hematopoiesis.
Martin-Rufino JD, Castano N, Pang M, Grody EI, Joubran S, Caulier A, Wahlster L, Li T, Qiu X, Riera-Escandell AM, Newby GA, Al'Khafaji A, Chaudhary S, Black S, Weng C, Munson G, Liu DR, Wlodarski MW, Sims K, Oakley JH, Fasano RM, Xavier RJ, Lander ES, Klein DE, Sankaran VG. Martin-Rufino JD, et al. Among authors: wahlster l. Cell. 2023 May 25;186(11):2456-2474.e24. doi: 10.1016/j.cell.2023.03.035. Epub 2023 May 2. Cell. 2023. PMID: 37137305 Free PMC article.
I SPI1 something needed for B cells.
Wahlster L, Sankaran VG. Wahlster L, et al. J Exp Med. 2021 Jul 5;218(7):e20210572. doi: 10.1084/jem.20210572. Epub 2021 May 12. J Exp Med. 2021. PMID: 33978700 Free PMC article.
32 results