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Human iPSC-based disease modeling studies identify a common mechanistic defect and potential therapies for AMD and related macular dystrophies.
Dalvi S, Roll M, Chatterjee A, Kumar LK, Bhogavalli A, Foley N, Arduino C, Spencer W, Reuben-Thomas C, Ortolan D, Pébay A, Bharti K, Anand-Apte B, Singh R. Dalvi S, et al. Among authors: reuben thomas c. Dev Cell. 2024 Sep 26:S1534-5807(24)00533-1. doi: 10.1016/j.devcel.2024.09.006. Online ahead of print. Dev Cell. 2024. PMID: 39362220
Genetic and cellular basis of impaired phagocytosis and photoreceptor degeneration in CLN3 disease.
Han J, Chear S, Talbot J, Swier V, Booth C, Reuben-Thomas C, Dalvi S, Weimer JM, Hewitt AW, Cook AL, Singh R. Han J, et al. Among authors: reuben thomas c. bioRxiv [Preprint]. 2024 Jun 13:2024.06.09.597388. doi: 10.1101/2024.06.09.597388. bioRxiv. 2024. Update in: Invest Ophthalmol Vis Sci. 2024 Nov 4;65(13):23. doi: 10.1167/iovs.65.13.23. PMID: 38895469 Free PMC article. Updated. Preprint.