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SLC6A19 inhibition facilitates urinary neutral amino acid excretion and lowers plasma phenylalanine.
Wobst HJ, Viader A, Muncipinto G, Hollibaugh R, van Kalken D, Burkhart CT, Cantin SM, Bates RM, Regimbald-Dumas Y, Gross L, Antalek MT, Zweig JE, Wu F, Rettenmaier TJ, Labenski MT, Pullen N, Blanchette HS, Henderson JL, Weng HH, Vaughn TA, Brown DG, Throup JP, Barrish JC. Wobst HJ, et al. Among authors: weng hh. JCI Insight. 2024 Nov 8;9(21):e182876. doi: 10.1172/jci.insight.182876. JCI Insight. 2024. PMID: 39513367 Clinical Trial.
NAT10-mediated mRNA N4-acetylcytidine reprograms serine metabolism to drive leukaemogenesis and stemness in acute myeloid leukaemia.
Zhang S, Huang F, Wang Y, Long Y, Li Y, Kang Y, Gao W, Zhang X, Wen Y, Wang Y, Pan L, Xia Y, Yang Z, Yang Y, Mo H, Li B, Hu J, Song Y, Zhang S, Dong S, Du X, Li Y, Liu Y, Liao W, Gao Y, Zhang Y, Chen H, Liang Y, Chen J, Weng H, Huang H. Zhang S, et al. Among authors: weng h. Nat Cell Biol. 2024 Nov 6. doi: 10.1038/s41556-024-01548-y. Online ahead of print. Nat Cell Biol. 2024. PMID: 39506072
ECM1 attenuates hepatic fibrosis by interfering with mediators of latent TGF-β1 activation.
Link F, Li Y, Zhao J, Munker S, Fan W, Nwosu ZC, Yao Y, Wang S, Huang C, Liebe R, Hammad S, Liu H, Shao C, Gao C, Sun B, Török NJ, Ding H, Ebert MP, Weng H, Ten Dijke P, Drasdo D, Dooley S, Wang S. Link F, et al. Among authors: weng h. Gut. 2024 Oct 24:gutjnl-2024-333213. doi: 10.1136/gutjnl-2024-333213. Online ahead of print. Gut. 2024. PMID: 39448254
1,638 results