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A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein.
Abu-Shmais AA, Guo L, Khalil AM, Miller RJ, Janke AK, Vukovich MJ, Bass LE, Suresh YP, Rush SA, Wolters RM, Kose N, Carnahan RH, Crowe JE, Bonami RH, Mousa JJ, McLellan JS, Georgiev IS. Abu-Shmais AA, et al. Among authors: carnahan rh. bioRxiv [Preprint]. 2024 Nov 1:2024.10.31.621295. doi: 10.1101/2024.10.31.621295. bioRxiv. 2024. PMID: 39554078 Free PMC article. Preprint.
Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors.
Cabel CR, Guzman BA, Alizadeh E, Li S, Holberg C, Wichaidit C, Cusanovich DA, Paek AL, Thatcher GRJ, Doorslaer KV, Nargi RS, Sutton RE, Suryadevara N, Crowe JE, Carnahan RH, Campos SK, Thorne CA. Cabel CR, et al. Among authors: carnahan rh. bioRxiv [Preprint]. 2024 Oct 7:2024.10.04.616743. doi: 10.1101/2024.10.04.616743. bioRxiv. 2024. PMID: 39416139 Free PMC article. Preprint.
Discovery and characterization of a pan-betacoronavirus S2-binding antibody.
Johnson NV, Wall SC, Kramer KJ, Holt CM, Periasamy S, Richardson SI, Manamela NP, Suryadevara N, Andreano E, Paciello I, Pierleoni G, Piccini G, Huang Y, Ge P, Allen JD, Uno N, Shiakolas AR, Pilewski KA, Nargi RS, Sutton RE, Abu-Shmais AA, Parks R, Haynes BF, Carnahan RH, Crowe JE Jr, Montomoli E, Rappuoli R, Bukreyev A, Ross TM, Sautto GA, McLellan JS, Georgiev IS. Johnson NV, et al. Among authors: carnahan rh. Structure. 2024 Nov 7;32(11):1893-1909.e11. doi: 10.1016/j.str.2024.08.022. Epub 2024 Sep 25. Structure. 2024. PMID: 39326419
Author Correction: Antibodies targeting the glycan cap of Ebola virus glycoprotein are potent inducers of the complement system.
Ilinykh PA, Huang K, Gunn BM, Kuzmina NA, Kedarinath K, Jurado-Cobena E, Zhou F, Subramani C, Hyde MA, Velazquez JV, Williamson LE, Gilchuk P, Carnahan RH, Alter G, Crowe JE Jr, Bukreyev A. Ilinykh PA, et al. Among authors: carnahan rh. Commun Biol. 2024 Jul 31;7(1):921. doi: 10.1038/s42003-024-06610-x. Commun Biol. 2024. PMID: 39085489 Free PMC article. No abstract available.
Antibodies targeting the glycan cap of Ebola virus glycoprotein are potent inducers of the complement system.
Ilinykh PA, Huang K, Gunn BM, Kuzmina NA, Kedarinath K, Jurado-Cobena E, Zhou F, Subramani C, Hyde MA, Velazquez JV, Williamson LE, Gilchuk P, Carnahan RH, Alter G, Crowe JE Jr, Bukreyev A. Ilinykh PA, et al. Among authors: carnahan rh. Commun Biol. 2024 Jul 17;7(1):871. doi: 10.1038/s42003-024-06556-0. Commun Biol. 2024. PMID: 39020082 Free PMC article.
Computationally restoring the potency of a clinical antibody against Omicron.
Desautels TA, Arrildt KT, Zemla AT, Lau EY, Zhu F, Ricci D, Cronin S, Zost SJ, Binshtein E, Scheaffer SM, Dadonaite B, Petersen BK, Engdahl TB, Chen E, Handal LS, Hall L, Goforth JW, Vashchenko D, Nguyen S, Weilhammer DR, Lo JK, Rubinfeld B, Saada EA, Weisenberger T, Lee TH, Whitener B, Case JB, Ladd A, Silva MS, Haluska RM, Grzesiak EA, Earnhart CG, Hopkins S, Bates TW, Thackray LB, Segelke BW; Tri-lab COVID-19 Consortium; Lillo AM, Sundaram S, Bloom JD, Diamond MS, Crowe JE Jr, Carnahan RH, Faissol DM. Desautels TA, et al. Among authors: carnahan rh. Nature. 2024 May;629(8013):878-885. doi: 10.1038/s41586-024-07385-1. Epub 2024 May 8. Nature. 2024. PMID: 38720086 Free PMC article.
Discovery and Characterization of a Pan-betacoronavirus S2-binding antibody.
Johnson NV, Wall SC, Kramer KJ, Holt CM, Periasamy S, Richardson S, Suryadevara N, Andreano E, Paciello I, Pierleoni G, Piccini G, Huang Y, Ge P, Allen JD, Uno N, Shiakolas AR, Pilewski KA, Nargi RS, Sutton RE, Abu-Shmais AA, Parks R, Haynes BF, Carnahan RH, Crowe JE Jr, Montomoli E, Rappuoli R, Bukreyev A, Ross TM, Sautto GA, McLellan JS, Georgiev IS. Johnson NV, et al. Among authors: carnahan rh. bioRxiv [Preprint]. 2024 Jan 16:2024.01.15.575741. doi: 10.1101/2024.01.15.575741. bioRxiv. 2024. Update in: Structure. 2024 Nov 7;32(11):1893-1909.e11. doi: 10.1016/j.str.2024.08.022. PMID: 38293237 Free PMC article. Updated. Preprint.
91 results