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180 results

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Page 1
A bitter anti-inflammatory drug binds at two distinct sites of a human bitter taste GPCR.
Peri L, Matzov D, Huxley DR, Rainish A, Fierro F, Sapir L, Pfeiffer T, Waterloo L, Hübner H, Peleg Y, Gmeiner P, McCormick PJ, Weikert D, Niv MY, Shalev-Benami M. Peri L, et al. Among authors: mccormick pj. Nat Commun. 2024 Nov 18;15(1):9991. doi: 10.1038/s41467-024-54157-6. Nat Commun. 2024. PMID: 39557861 Free PMC article.
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy.
Yang T, Li J, Cheng X, Lu Q, Farooq Z, Fu Y, Lv S, Nan W, Yu B, Duan J, Zhang Y, Fu Y, Jiang H, McCormick PJ, Li Y, Zhang J. Yang T, et al. Among authors: mccormick pj. J Struct Biol. 2024 Sep;216(3):108117. doi: 10.1016/j.jsb.2024.108117. Epub 2024 Aug 15. J Struct Biol. 2024. PMID: 39153560
Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists.
Kosar M, Sarott RC, Sykes DA, Viray AEG, Vitale RM, Tomašević N, Li X, Ganzoni RLZ, Kicin B, Reichert L, Patej KJ, Gómez-Bouzó U, Guba W, McCormick PJ, Hua T, Gruber CW, Veprintsev DB, Frank JA, Grether U, Carreira EM. Kosar M, et al. Among authors: mccormick pj. ACS Cent Sci. 2024 Mar 11;10(5):956-968. doi: 10.1021/acscentsci.3c01461. eCollection 2024 May 22. ACS Cent Sci. 2024. PMID: 38799662 Free PMC article.
Correction to: A1R-A2AR heteromers coupled to Gs and Gi/0 proteins modulate GABA transport into astrocytes.
Cristóvão-Ferreira S, Navarro G, Brugarolas M, Pérez-Capote K, Vaz SH, Fattorini G, Conti F, Lluis C, Ribeiro JA, McCormick PJ, Casadó V, Franco R, Sebastião AM. Cristóvão-Ferreira S, et al. Among authors: mccormick pj. Purinergic Signal. 2024 Jun;20(3):315-316. doi: 10.1007/s11302-024-10012-3. Purinergic Signal. 2024. PMID: 38671309 Free PMC article. No abstract available.
Cryo-EM structure of human HCN3 channel and its regulation by cAMP.
Yu B, Lu Q, Li J, Cheng X, Hu H, Li Y, Che T, Hua Y, Jiang H, Zhang Y, Xian C, Yang T, Fu Y, Chen Y, Nan W, McCormick PJ, Xiong B, Duan J, Zeng B, Li Y, Fu Y, Zhang J. Yu B, et al. Among authors: mccormick pj. J Biol Chem. 2024 Jun;300(6):107288. doi: 10.1016/j.jbc.2024.107288. Epub 2024 Apr 16. J Biol Chem. 2024. PMID: 38636662 Free PMC article.
Variability in Intraoperative Opioid and Nonopioid Utilization During Intracranial Surgery: A Multicenter, Retrospective Cohort Study.
Naik BI, Lele AV, Sharma D, Akkermans A, Vlisides PE, Colquhoun DA, Domino KB, Tsang S, Sun E, Dunn LK; Multicenter Perioperative Outcomes Collaborator Group. Naik BI, et al. J Neurosurg Anesthesiol. 2024 Mar 28:10.1097/ANA.0000000000000960. doi: 10.1097/ANA.0000000000000960. Online ahead of print. J Neurosurg Anesthesiol. 2024. PMID: 38546217
180 results