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A novel phosphodiesterase 5 inhibitor, RF26, improves memory impairment and ameliorates tau aggregation and neuroinflammation in the P301S tauopathy mouse model of Alzheimer's disease.
El-Desouky S, Abdel-Halim M, Fathalla RK, Abadi AH, Piazza GA, Salama M, El-Khodery SA, Youssef MA, Elfarrash S. El-Desouky S, et al. Among authors: salama m. Exp Neurol. 2024 Nov 14;384:115058. doi: 10.1016/j.expneurol.2024.115058. Online ahead of print. Exp Neurol. 2024. PMID: 39549949
The p.Gly2019Ser is a common LRRK2 pathogenic variant among Egyptians with familial and sporadic Parkinson's disease.
William MB, Hamed S, Shalash A, Khedr EM, Yousef MH, El-Jaafary S, Fawi G, Helmy A, Hamid E, Essam M, Lee H, Jama A, Koraym M, Mahmoud DM, Elfarrash S, Elsaid Y, Gabr AS, Shebl N, Abdelwahhab N, Belal TM, Elsayed NAB, El-Gamal M, Elgamal S, Ragab S, Mekky J, Aly L, Nabhan S, Ragab G, Hussein MA, Hegazy MT, Houlden H, Salama M, Rizig M. William MB, et al. Among authors: salama m. NPJ Parkinsons Dis. 2024 Nov 6;10(1):215. doi: 10.1038/s41531-024-00826-8. NPJ Parkinsons Dis. 2024. PMID: 39505921 Free PMC article.
894 results