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A Structural Mechanism for Noncanonical GPCR Signal Transduction in the Hedgehog Pathway.
Steiner WP, Iverson N, Venkatakrishnan V, Wu J, Stepniewski TM, Michaelson Z, Bröckel JW, Zhu JF, Bruystens J, Lee A, Nelson I, Bertinetti D, Arveseth CD, Tan G, Spaltenstein P, Xu J, Hüttenhain R, Kay M, Herberg FW, Selent J, Anand GS, Dunbrack RL, Taylor SS, Myers BR. Steiner WP, et al. Among authors: herberg fw. bioRxiv [Preprint]. 2024 Nov 1:2024.10.31.621410. doi: 10.1101/2024.10.31.621410. bioRxiv. 2024. PMID: 39554190 Free PMC article. Preprint.
RedOx regulation of LRRK2 kinase activity by active site cysteines.
Trilling CR, Weng JH, Sharma PK, Nolte V, Wu J, Ma W, Boassa D, Taylor SS, Herberg FW. Trilling CR, et al. Among authors: herberg fw. NPJ Parkinsons Dis. 2024 Apr 3;10(1):75. doi: 10.1038/s41531-024-00683-5. NPJ Parkinsons Dis. 2024. PMID: 38570484 Free PMC article.
Corrigendum to "Novel LRR-ROC Motif That Links the N- and C-terminal Domains in LRRK2 Undergoes an Order-Disorder Transition Upon Activation" [J. Mol. Biol. 435(12) (2023) 1-17].
Weng JH, Trilling CR, Kaila Sharma P, Störmer E, Wu J, Herberg FW, Taylor SS. Weng JH, et al. Among authors: herberg fw. J Mol Biol. 2024 Mar 15;436(6):168485. doi: 10.1016/j.jmb.2024.168485. Epub 2024 Feb 17. J Mol Biol. 2024. PMID: 38369414 Free article. No abstract available.
Capturing the domain crosstalk in full length LRRK2 and LRRK2RCKW.
Störmer E, Weng JH, Wu J, Bertinetti D, Kaila Sharma P, Ma W, Herberg FW, Taylor S. Störmer E, et al. Among authors: herberg fw. Biochem J. 2023 May 22;480(11):815-33. doi: 10.1042/BCJ20230126. Online ahead of print. Biochem J. 2023. PMID: 37212165 Free PMC article.
146 results