Barry PH - Search Results

1

The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element.

Rajendra S, Vandenberg RJ, Pierce KD, Cunningham AM, French PW, Barry PH, Schofield PR. Rajendra S, et al. Among authors: barry ph. EMBO J. 1995 Jul 3;14(13):2987-98. doi: 10.1002/j.1460-2075.1995.tb07301.x. EMBO J. 1995. PMID: 7621814 Free PMC article.

2

Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity.

Keramidas A, Moorhouse AJ, Pierce KD, Schofield PR, Barry PH. Keramidas A, et al. Among authors: barry ph. J Gen Physiol. 2002 May;119(5):393-410. doi: 10.1085/jgp.20028552. J Gen Physiol. 2002. PMID: 11981020 Free PMC article.

3

Startle disease mutations reduce the agonist sensitivity of the human inhibitory glycine receptor.

Rajendra S, Lynch JW, Pierce KD, French CR, Barry PH, Schofield PR. Rajendra S, et al. Among authors: barry ph. J Biol Chem. 1994 Jul 22;269(29):18739-42. J Biol Chem. 1994. PMID: 7518444 Free article.

4

Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator.

Lynch JW, Rajendra S, Barry PH, Schofield PR. Lynch JW, et al. Among authors: barry ph. J Biol Chem. 1995 Jun 9;270(23):13799-806. doi: 10.1074/jbc.270.23.13799. J Biol Chem. 1995. PMID: 7775436 Free article.

5

Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists.

Rajendra S, Lynch JW, Pierce KD, French CR, Barry PH, Schofield PR. Rajendra S, et al. Among authors: barry ph. Neuron. 1995 Jan;14(1):169-75. doi: 10.1016/0896-6273(95)90251-1. Neuron. 1995. PMID: 7826634 Free article.

6

The extracellular disulfide loop motif of the inhibitory glycine receptor does not form the agonist binding site.

Vandenberg RJ, Rajendra S, French CR, Barry PH, Schofield PR. Vandenberg RJ, et al. Among authors: barry ph. Mol Pharmacol. 1993 Jul;44(1):198-203. Mol Pharmacol. 1993. PMID: 8393521

7

Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel.

Lynch JW, Rajendra S, Pierce KD, Handford CA, Barry PH, Schofield PR. Lynch JW, et al. Among authors: barry ph. EMBO J. 1997 Jan 2;16(1):110-20. doi: 10.1093/emboj/16.1.110. EMBO J. 1997. PMID: 9009272 Free PMC article.

8

Molecular and genetic insights into ligand binding and signal transduction at the inhibitory glycine receptor.

Schofield PR, Lynch JW, Rajendra S, Pierce KD, Handford CA, Barry PH. Schofield PR, et al. Among authors: barry ph. Cold Spring Harb Symp Quant Biol. 1996;61:333-42. Cold Spring Harb Symp Quant Biol. 1996. PMID: 9246463 No abstract available.

9

Glycine receptors: what gets in and why?

Barry PH, Schofield PR, Moorhouse AJ. Barry PH, et al. Clin Exp Pharmacol Physiol. 1999 Nov;26(11):935-6. doi: 10.1046/j.1440-1681.1999.03149.x. Clin Exp Pharmacol Physiol. 1999. PMID: 10561819 Review.

10

Antagonism of ligand-gated ion channel receptors: two domains of the glycine receptor alpha subunit form the strychnine-binding site.

Vandenberg RJ, French CR, Barry PH, Shine J, Schofield PR. Vandenberg RJ, et al. Among authors: barry ph. Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1765-9. doi: 10.1073/pnas.89.5.1765. Proc Natl Acad Sci U S A. 1992. PMID: 1311851 Free PMC article.

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