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The functional microdomain in transmembrane helices 2 and 7 regulates expression, activation, and coupling pathways of the gonadotropin-releasing hormone receptor.
Flanagan CA, Zhou W, Chi L, Yuen T, Rodic V, Robertson D, Johnson M, Holland P, Millar RP, Weinstein H, Mitchell R, Sealfon SC. Flanagan CA, et al. Among authors: sealfon sc. J Biol Chem. 1999 Oct 8;274(41):28880-6. doi: 10.1074/jbc.274.41.28880. J Biol Chem. 1999. PMID: 10506131 Free article.
A chicken gonadotropin-releasing hormone receptor that confers agonist activity to mammalian antagonists. Identification of D-Lys(6) in the ligand and extracellular loop two of the receptor as determinants.
Sun YM, Flanagan CA, Illing N, Ott TR, Sellar R, Fromme BJ, Hapgood J, Sharp P, Sealfon SC, Millar RP. Sun YM, et al. Among authors: sealfon sc. J Biol Chem. 2001 Mar 16;276(11):7754-61. doi: 10.1074/jbc.M009020200. Epub 2000 Dec 8. J Biol Chem. 2001. PMID: 11112780 Free article.
Comparative sequence analysis and functional characterization of the cloned sheep gonadotropin-releasing hormone receptor reveal differences in primary structure and ligand specificity among mammalian receptors.
Illing N, Jacobs GF, Becker II, Flanagan CA, Davidson JS, Eales A, Zhou W, Sealfon SC, Millar RP. Illing N, et al. Among authors: sealfon sc. Biochem Biophys Res Commun. 1993 Oct 29;196(2):745-51. doi: 10.1006/bbrc.1993.2312. Biochem Biophys Res Commun. 1993. PMID: 7694577
251 results