Liu EC - Search Results

1

Structure-activity studies of endothelin leading to novel peptide ETA antagonists.

Hunt JT, Lee VG, McMullen D, Liu EC, Bolgar M, Delaney CL, Festin SM, Floyd DM, Hedberg A, Natarajan S, et al. Hunt JT, et al. Among authors: liu ec. Bioorg Med Chem. 1993 Jul;1(1):59-65. doi: 10.1016/s0968-0896(00)82103-3. Bioorg Med Chem. 1993. PMID: 8081838

2

Site-specific biotinylation. A novel approach and its application to endothelin-1 analogs and PTH-analog.

Natarajan S, Festin SM, Hedberg A, Liu EC, Floyd DM, Hunt JT. Natarajan S, et al. Among authors: liu ec. Int J Pept Protein Res. 1992 Dec;40(6):567-74. Int J Pept Protein Res. 1992. PMID: 1286942

3

Discovery and structure-activity relationships of sulfonamide ETA-selective antagonists.

Stein PD, Floyd DM, Bisaha S, Dickey J, Girotra RN, Gougoutas JZ, Kozlowski M, Lee VG, Liu EC, Malley MF, et al. Stein PD, et al. Among authors: liu ec. J Med Chem. 1995 Apr 14;38(8):1344-54. doi: 10.1021/jm00008a013. J Med Chem. 1995. PMID: 7731020

4

The receptor binding affinity of monocyclic [Ala3,Xaa11]endothelin-1 analogs correlates with inducible helix length.

Andersen NH, Harris SM, Lee VG, Liu EC, Moreland S, Hunt JT. Andersen NH, et al. Among authors: liu ec. Bioorg Med Chem. 1995 Feb;3(2):113-24. doi: 10.1016/0968-0896(95)00005-2. Bioorg Med Chem. 1995. PMID: 7796045

5

Control of peptide disulfide regioisomer formation by mixed cysteine-penicillamine bridges. Application to endothelin-1.

Hunt JT, Lee VG, Liu EC, Moreland S, McMullen D, Webb ML, Bolgar M. Hunt JT, et al. Among authors: liu ec. Int J Pept Protein Res. 1993 Sep;42(3):249-58. doi: 10.1111/j.1399-3011.1993.tb00139.x. Int J Pept Protein Res. 1993. PMID: 8225780

6

The discovery of sulfonamide endothelin antagonists and the development of the orally active ETA antagonist 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulf onamide.

Stein PD, Hunt JT, Floyd DM, Moreland S, Dickinson KE, Mitchell C, Liu EC, Webb ML, Murugesan N, Dickey J, et al. Stein PD, et al. Among authors: liu ec. J Med Chem. 1994 Feb 4;37(3):329-31. doi: 10.1021/jm00029a001. J Med Chem. 1994. PMID: 8308857 No abstract available.

7

Biphenylsulfonamide endothelin antagonists: structure-activity relationships of a series of mono- and disubstituted analogues and pharmacology of the orally active endothelin antagonist 2'-amino-N- (3,4-dimethyl-5-isoxazolyl)-4'-(2-methylpropyl)[1, 1'-biphenyl]-2-sulfonamide (BMS-187308).

Murugesan N, Gu Z, Stein PD, Bisaha S, Spergel S, Girotra R, Lee VG, Lloyd J, Misra RN, Schmidt J, Mathur A, Stratton L, Kelly YF, Bird E, Waldron T, Liu EC, Zhang R, Lee H, Serafino R, Abboa-Offei B, Mathers P, Giancarli M, Seymour AA, Webb ML, Hunt JT, et al. Murugesan N, et al. Among authors: liu ec. J Med Chem. 1998 Dec 17;41(26):5198-218. doi: 10.1021/jm970872k. J Med Chem. 1998. PMID: 9857090

8

DuP 753, the selective angiotensin II receptor blocker, is a competitive antagonist to human platelet thromboxane A2/prostaglandin H2 (TP) receptors.

Liu EC, Hedberg A, Goldenberg HJ, Harris DN, Webb ML. Liu EC, et al. Prostaglandins. 1992 Aug;44(2):89-99. doi: 10.1016/0090-6980(92)90070-a. Prostaglandins. 1992. PMID: 1438880

9

Vascular A10 cell membranes contain an endothelin metabolizing neutral endopeptidase.

Dickinson KE, Tymiak AA, Cohen RB, Liu EC, Webb ML, Hedberg A. Dickinson KE, et al. Among authors: liu ec. Biochem Biophys Res Commun. 1991 Apr 15;176(1):423-30. doi: 10.1016/0006-291x(91)90941-y. Biochem Biophys Res Commun. 1991. PMID: 2018530

10

The endothelin receptor antagonist, BQ-123, inhibits angiotensin II-induced contractions in rabbit aorta.

Webb ML, Dickinson KE, Delaney CL, Liu EC, Serafino R, Cohen RB, Monshizadegan H, Moreland S. Webb ML, et al. Among authors: liu ec. Biochem Biophys Res Commun. 1992 Jun 30;185(3):887-92. doi: 10.1016/0006-291x(92)91710-8. Biochem Biophys Res Commun. 1992. PMID: 1320879

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