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Page 1
Exploration of the P2-P3 SAR of aldehyde cathepsin K inhibitors.
Boros EE, Deaton DN, Hassell AM, McFadyen RB, Miller AB, Miller LR, Paulick MG, Shewchuk LM, Thompson JB, Willard DH Jr, Wright LL. Boros EE, et al. Among authors: deaton dn. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3425-9. doi: 10.1016/j.bmcl.2004.04.084. Bioorg Med Chem Lett. 2004. PMID: 15177446
Exploration of the P1 SAR of aldehyde cathepsin K inhibitors.
Catalano JG, Deaton DN, Furfine ES, Hassell AM, McFadyen RB, Miller AB, Miller LR, Shewchuk LM, Willard DH Jr, Wright LL. Catalano JG, et al. Among authors: deaton dn. Bioorg Med Chem Lett. 2004 Jan 5;14(1):275-8. doi: 10.1016/j.bmcl.2003.09.088. Bioorg Med Chem Lett. 2004. PMID: 14684342
A structural screening approach to ketoamide-based inhibitors of cathepsin K.
Barrett DG, Catalano JG, Deaton DN, Long ST, McFadyen RB, Miller AB, Miller LR, Wells-Knecht KJ, Wright LL. Barrett DG, et al. Among authors: deaton dn. Bioorg Med Chem Lett. 2005 May 2;15(9):2209-13. doi: 10.1016/j.bmcl.2005.03.023. Bioorg Med Chem Lett. 2005. PMID: 15837295
Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?
Adkison KK, Barrett DG, Deaton DN, Gampe RT, Hassell AM, Long ST, McFadyen RB, Miller AB, Miller LR, Payne JA, Shewchuk LM, Wells-Knecht KJ, Willard DH Jr, Wright LL. Adkison KK, et al. Among authors: deaton dn. Bioorg Med Chem Lett. 2006 Feb 15;16(4):978-83. doi: 10.1016/j.bmcl.2005.10.108. Epub 2005 Nov 15. Bioorg Med Chem Lett. 2006. PMID: 16290936
Novel, potent P2-P3 pyrrolidine derivatives of ketoamide-based cathepsin K inhibitors.
Barrett DG, Catalano JG, Deaton DN, Hassell AM, Long ST, Miller AB, Miller LR, Ray JA, Samano V, Shewchuk LM, Wells-Knecht KJ, Willard DH Jr, Wright LL. Barrett DG, et al. Among authors: deaton dn. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1735-9. doi: 10.1016/j.bmcl.2005.11.101. Epub 2006 Jan 11. Bioorg Med Chem Lett. 2006. PMID: 16376075
38 results