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Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease.
Rockenstein EM, McConlogue L, Tan H, Power M, Masliah E, Mucke L. Rockenstein EM, et al. Among authors: mucke l. J Biol Chem. 1995 Nov 24;270(47):28257-67. doi: 10.1074/jbc.270.47.28257. J Biol Chem. 1995. PMID: 7499323 Free article.
Recently, a transgenic model was established in which platelet-derived growth factor (PDGF) promoter-driven neuronal expression of an alternatively spliced hAPP minigene resulted in prominent AD-type neuropathology (Games, D., Adams, D., Alessandrini, R., Barbour, R., Berthelette …
Recently, a transgenic model was established in which platelet-derived growth factor (PDGF) promoter-driven neuronal expression of an altern …
gp120 and neurotoxicity in vivo.
Lipton SA, Brenneman DE, Silverstein FS, Masliah E, Mucke L. Lipton SA, et al. Among authors: mucke l. Trends Pharmacol Sci. 1995 Apr;16(4):122. doi: 10.1016/s0165-6147(00)88998-1. Trends Pharmacol Sci. 1995. PMID: 7610496 No abstract available.
Protection against HIV-1 gp120-induced brain damage by neuronal expression of human amyloid precursor protein.
Mucke L, Abraham CR, Ruppe MD, Rockenstein EM, Toggas SM, Mallory M, Alford M, Masliah E. Mucke L, et al. J Exp Med. 1995 Apr 1;181(4):1551-6. doi: 10.1084/jem.181.4.1551. J Exp Med. 1995. PMID: 7699335 Free PMC article.
Rockenstein, G. F. Rall, C. R. Abraham, and L. Mucke. 1994. Nature [Lond.]. 367:188-193.). To further analyze the pathogenesis of gp120-induced neurotoxicity and to assess the neuroprotective potential of human amyloid precursor proteins (hAPPs) in vivo, different h …
Rockenstein, G. F. Rall, C. R. Abraham, and L. Mucke. 1994. Nature [Lond.]. 367:188-193.). To further analyze the pathogenesis …
177 results