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Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors. Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling.
Rani CS, Wang F, Fuior E, Berger A, Wu J, Sturgill TW, Beitner-Johnson D, LeRoith D, Varticovski L, Spiegel S. Rani CS, et al. Among authors: wang f. J Biol Chem. 1997 Apr 18;272(16):10777-83. doi: 10.1074/jbc.272.16.10777. J Biol Chem. 1997. PMID: 9099730 Free article.
Sphingosine-1-phosphate in cell growth and cell death.
Spiegel S, Cuvillier O, Edsall LC, Kohama T, Menzeleev R, Olah Z, Olivera A, Pirianov G, Thomas DM, Tu Z, Van Brocklyn JR, Wang F. Spiegel S, et al. Among authors: wang f. Ann N Y Acad Sci. 1998 Jun 19;845:11-8. doi: 10.1111/j.1749-6632.1998.tb09658.x. Ann N Y Acad Sci. 1998. PMID: 9668339 Review.
Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis.
Wang F, Van Brocklyn JR, Hobson JP, Movafagh S, Zukowska-Grojec Z, Milstien S, Spiegel S. Wang F, et al. J Biol Chem. 1999 Dec 10;274(50):35343-50. doi: 10.1074/jbc.274.50.35343. J Biol Chem. 1999. PMID: 10585401 Free article.
In agreement with previous findings in human breast cancer cells (Wang, F., Nohara, K., Olivera, O., Thompson, E. W., and Spiegel, S. (1999) Exp. Cell Res. 247, 17-28), SPP, at micromolar concentrations, inhibited chemotaxis of both vector- and EDG-1-overexpressing …
In agreement with previous findings in human breast cancer cells (Wang, F., Nohara, K., Olivera, O., Thompson, E. W., and Spie …
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