Hensgens CM - Search Results

1

Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.

Roach PL, Clifton IJ, Hensgens CM, Shibata N, Schofield CJ, Hajdu J, Baldwin JE. Roach PL, et al. Among authors: hensgens cm. Nature. 1997 Jun 19;387(6635):827-30. doi: 10.1038/42990. Nature. 1997. PMID: 9194566

2

Proteins of the penicillin biosynthesis pathway.

Schofield CJ, Baldwin JE, Byford MF, Clifton I, Hajdu J, Hensgens C, Roach P. Schofield CJ, et al. Curr Opin Struct Biol. 1997 Dec;7(6):857-64. doi: 10.1016/s0959-440x(97)80158-3. Curr Opin Struct Biol. 1997. PMID: 9434907 Review.

3

Anaerobic crystallisation of an isopenicillin N synthase.Fe(II).substrate complex demonstrated by X-ray studies.

Roach PL, Clifton IJ, Hensgens CM, Shibata N, Long AJ, Strange RW, Hasnain SS, Schofield CJ, Baldwin JE, Hajdu J. Roach PL, et al. Among authors: hensgens cm. Eur J Biochem. 1996 Dec 15;242(3):736-40. doi: 10.1111/j.1432-1033.1996.0736r.x. Eur J Biochem. 1996. PMID: 9022704 Free article.

4

The reaction cycle of isopenicillin N synthase observed by X-ray diffraction.

Burzlaff NI, Rutledge PJ, Clifton IJ, Hensgens CM, Pickford M, Adlington RM, Roach PL, Baldwin JE. Burzlaff NI, et al. Among authors: hensgens cm. Nature. 1999 Oct 14;401(6754):721-4. doi: 10.1038/44400. Nature. 1999. PMID: 10537113

5

Controlling the substrate selectivity of deacetoxycephalosporin/deacetylcephalosporin C synthase.

Lloyd MD, Lipscomb SJ, Hewitson KS, Hensgens CM, Baldwin JE, Schofield CJ. Lloyd MD, et al. Among authors: hensgens cm. J Biol Chem. 2004 Apr 9;279(15):15420-6. doi: 10.1074/jbc.M313928200. Epub 2004 Jan 20. J Biol Chem. 2004. PMID: 14734549 Free article.

6

Studies on non-haem ferrous-dependent oxygenases and oxidases.

Barlow JN, Baldwin JE, Clifton IJ, Gibson E, Hensgens CM, Hajdu J, Hara T, Hassan A, John P, Lloyd MD, Roach PL, Prescott A, Robinson JK, Zhang ZH, Schofield CJ. Barlow JN, et al. Among authors: hensgens cm. Biochem Soc Trans. 1997 Feb;25(1):86-90. doi: 10.1042/bst0250086. Biochem Soc Trans. 1997. PMID: 9056849 Review. No abstract available.

7

The sequence and crystal structure of the alpha-amino acid ester hydrolase from Xanthomonas citri define a new family of beta-lactam antibiotic acylases.

Barends TR, Polderman-Tijmes JJ, Jekel PA, Hensgens CM, de Vries EJ, Janssen DB, Dijkstra BW. Barends TR, et al. Among authors: hensgens cm. J Biol Chem. 2003 Jun 20;278(25):23076-84. doi: 10.1074/jbc.M302246200. Epub 2003 Apr 8. J Biol Chem. 2003. PMID: 12684501 Free article.

8

Structures of an isopenicillin N converting Ntn-hydrolase reveal different catalytic roles for the active site residues of precursor and mature enzyme.

Bokhove M, Yoshida H, Hensgens CM, van der Laan JM, Sutherland JD, Dijkstra BW. Bokhove M, et al. Among authors: hensgens cm. Structure. 2010 Mar 10;18(3):301-8. doi: 10.1016/j.str.2010.01.005. Structure. 2010. PMID: 20223213 Free article.

9

Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.

Alkema WB, Hensgens CM, Kroezinga EH, de Vries E, Floris R, van der Laan JM, Dijkstra BW, Janssen DB. Alkema WB, et al. Among authors: hensgens cm. Protein Eng. 2000 Dec;13(12):857-63. doi: 10.1093/protein/13.12.857. Protein Eng. 2000. PMID: 11239085

10

Purification and properties of 5,10-methylenetetrahydromethanopterin reductase, a coenzyme F420-dependent enzyme, from Methanobacterium thermoautotrophicum strain delta H.

te Brömmelstroet BW, Hensgens CM, Keltjens JT, van der Drift C, Vogels GD. te Brömmelstroet BW, et al. Among authors: hensgens cm. J Biol Chem. 1990 Feb 5;265(4):1852-7. J Biol Chem. 1990. PMID: 2298726 Free article.

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