Schinkel AH - Search Results

1

Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833.

Mayer U, Wagenaar E, Dorobek B, Beijnen JH, Borst P, Schinkel AH. Mayer U, et al. Among authors: schinkel ah. J Clin Invest. 1997 Nov 15;100(10):2430-6. doi: 10.1172/JCI119784. J Clin Invest. 1997. PMID: 9366556 Free PMC article.

2

Characterization of the human MDR3 P-glycoprotein and its recognition by P-glycoprotein-specific monoclonal antibodies.

Schinkel AH, Roelofs EM, Borst P. Schinkel AH, et al. Cancer Res. 1991 May 15;51(10):2628-35. Cancer Res. 1991. PMID: 1673638

3

Multidrug resistance mediated by P-glycoproteins.

Schinkel AH, Borst P. Schinkel AH, et al. Semin Cancer Biol. 1991 Aug;2(4):213-26. Semin Cancer Biol. 1991. PMID: 1680493 Review.

4

Resistance to natural products in leukemia.

Borst P, Baas F, Lincke CR, Schinkel AH, Smit JJ, Van der Velde-Koerts T. Borst P, et al. Among authors: schinkel ah. Bone Marrow Transplant. 1990 Jul;6 Suppl 1:44-7. Bone Marrow Transplant. 1990. PMID: 1975205 Review. No abstract available.

5

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

Schinkel AH, Wagenaar E, van Deemter L, Mol CA, Borst P. Schinkel AH, et al. J Clin Invest. 1995 Oct;96(4):1698-705. doi: 10.1172/JCI118214. J Clin Invest. 1995. PMID: 7560060 Free PMC article.

6

Multidrug resistance and the role of P-glycoprotein knockout mice.

Schinkel AH, Mol CA, Wagenaar E, van Deemter L, Smit JJ, Borst P. Schinkel AH, et al. Eur J Cancer. 1995 Jul-Aug;31A(7-8):1295-8. doi: 10.1016/0959-8049(95)00130-b. Eur J Cancer. 1995. PMID: 7577039 Review.

7

Tissue distribution of the human MDR3 P-glycoprotein.

Smit JJ, Schinkel AH, Mol CA, Majoor D, Mooi WJ, Jongsma AP, Lincke CR, Borst P. Smit JJ, et al. Among authors: schinkel ah. Lab Invest. 1994 Nov;71(5):638-49. Lab Invest. 1994. PMID: 7734012

8

Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.

Oude Elferink RP, Ottenhoff R, van Wijland M, Smit JJ, Schinkel AH, Groen AK. Oude Elferink RP, et al. Among authors: schinkel ah. J Clin Invest. 1995 Jan;95(1):31-8. doi: 10.1172/JCI117658. J Clin Invest. 1995. PMID: 7814632 Free PMC article.

9

Characterization of the promoter region of the human MDR3 P-glycoprotein gene.

Smit JJ, Mol CA, van Deemter L, Wagenaar E, Schinkel AH, Borst P. Smit JJ, et al. Among authors: schinkel ah. Biochim Biophys Acta. 1995 Mar 14;1261(1):44-56. doi: 10.1016/0167-4781(94)00214-n. Biochim Biophys Acta. 1995. PMID: 7893760

10

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs.

Schinkel AH, Smit JJ, van Tellingen O, Beijnen JH, Wagenaar E, van Deemter L, Mol CA, van der Valk MA, Robanus-Maandag EC, te Riele HP, et al. Schinkel AH, et al. Cell. 1994 May 20;77(4):491-502. doi: 10.1016/0092-8674(94)90212-7. Cell. 1994. PMID: 7910522

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