Akopian T - Search Results

1

Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide.

Craiu A, Akopian T, Goldberg A, Rock KL. Craiu A, et al. Among authors: akopian t. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10850-5. doi: 10.1073/pnas.94.20.10850. Proc Natl Acad Sci U S A. 1997. PMID: 9380723 Free PMC article.

2

Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation.

Craiu A, Gaczynska M, Akopian T, Gramm CF, Fenteany G, Goldberg AL, Rock KL. Craiu A, et al. Among authors: akopian t. J Biol Chem. 1997 May 16;272(20):13437-45. doi: 10.1074/jbc.272.20.13437. J Biol Chem. 1997. PMID: 9148969 Free article.

3

Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase.

Saric T, Beninga J, Graef CI, Akopian TN, Rock KL, Goldberg AL. Saric T, et al. Among authors: akopian tn. J Biol Chem. 2001 Sep 28;276(39):36474-81. doi: 10.1074/jbc.M105517200. Epub 2001 Jul 30. J Biol Chem. 2001. PMID: 11479311 Free article.

4

Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum.

Akopian TN, Kisselev AF, Goldberg AL. Akopian TN, et al. J Biol Chem. 1997 Jan 17;272(3):1791-8. doi: 10.1074/jbc.272.3.1791. J Biol Chem. 1997. PMID: 8999862 Free article.

5

New insights into the mechanisms and importance of the proteasome in intracellular protein degradation.

Goldberg AL, Akopian TN, Kisselev AF, Lee DH, Rohrwild M. Goldberg AL, et al. Among authors: akopian tn. Biol Chem. 1997 Mar-Apr;378(3-4):131-40. Biol Chem. 1997. PMID: 9165063 Review.

6

Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes.

Kisselev AF, Akopian TN, Goldberg AL. Kisselev AF, et al. Among authors: akopian tn. J Biol Chem. 1998 Jan 23;273(4):1982-9. doi: 10.1074/jbc.273.4.1982. J Biol Chem. 1998. PMID: 9442034 Free article.

7

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation.

Kisselev AF, Akopian TN, Woo KM, Goldberg AL. Kisselev AF, et al. Among authors: akopian tn. J Biol Chem. 1999 Feb 5;274(6):3363-71. doi: 10.1074/jbc.274.6.3363. J Biol Chem. 1999. PMID: 9920878 Free article.

8

Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown.

Kisselev AF, Akopian TN, Castillo V, Goldberg AL. Kisselev AF, et al. Among authors: akopian tn. Mol Cell. 1999 Sep;4(3):395-402. doi: 10.1016/s1097-2765(00)80341-x. Mol Cell. 1999. PMID: 10518220 Free article.

9

Protein degradation by the proteasome and dissection of its in vivo importance with synthetic inhibitors.

Goldberg AL, Akopian TN, Kisselev AF, Lee DH. Goldberg AL, et al. Among authors: akopian tn. Mol Biol Rep. 1997 Mar;24(1-2):69-75. doi: 10.1023/a:1006860828265. Mol Biol Rep. 1997. PMID: 9228284 Review. No abstract available.

10

The active ClpP protease from M. tuberculosis is a complex composed of a heptameric ClpP1 and a ClpP2 ring.

Akopian T, Kandror O, Raju RM, Unnikrishnan M, Rubin EJ, Goldberg AL. Akopian T, et al. EMBO J. 2012 Mar 21;31(6):1529-41. doi: 10.1038/emboj.2012.5. Epub 2012 Jan 27. EMBO J. 2012. PMID: 22286948 Free PMC article.

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