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HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies.
Connors M, Kovacs JA, Krevat S, Gea-Banacloche JC, Sneller MC, Flanigan M, Metcalf JA, Walker RE, Falloon J, Baseler M, Feuerstein I, Masur H, Lane HC. Connors M, et al. Among authors: flanigan m. Nat Med. 1997 May;3(5):533-40. doi: 10.1038/nm0597-533. Nat Med. 1997. PMID: 9142122
Resistance to replication of human immunodeficiency virus challenge in SCID-Hu mice engrafted with peripheral blood mononuclear cells of nonprogressors is mediated by CD8(+) T cells and associated with a proliferative response to p24 antigen.
de Quiros JC, Shupert WL, McNeil AC, Gea-Banacloche JC, Flanigan M, Savage A, Martino L, Weiskopf EE, Imamichi H, Zhang YM, Adelsburger J, Stevens R, Murphy PM, Zimmerman PA, Hallahan CW, Davey RT Jr, Connors M. de Quiros JC, et al. Among authors: flanigan m. J Virol. 2000 Feb;74(4):2023-8. doi: 10.1128/jvi.74.4.2023-2028.2000. J Virol. 2000. PMID: 10644376 Free PMC article.
Loss of metabotropic glutamate receptor 2 escalates alcohol consumption.
Zhou Z, Karlsson C, Liang T, Xiong W, Kimura M, Tapocik JD, Yuan Q, Barbier E, Feng A, Flanigan M, Augier E, Enoch MA, Hodgkinson CA, Shen PH, Lovinger DM, Edenberg HJ, Heilig M, Goldman D. Zhou Z, et al. Among authors: flanigan m. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16963-8. doi: 10.1073/pnas.1309839110. Epub 2013 Sep 30. Proc Natl Acad Sci U S A. 2013. PMID: 24082084 Free PMC article.
Basal forebrain projections to the lateral habenula modulate aggression reward.
Golden SA, Heshmati M, Flanigan M, Christoffel DJ, Guise K, Pfau ML, Aleyasin H, Menard C, Zhang H, Hodes GE, Bregman D, Khibnik L, Tai J, Rebusi N, Krawitz B, Chaudhury D, Walsh JJ, Han MH, Shapiro ML, Russo SJ. Golden SA, et al. Among authors: flanigan m. Nature. 2016 Jun 30;534(7609):688-92. doi: 10.1038/nature18601. Nature. 2016. PMID: 27357796 Free PMC article.
Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats.
Schank JR, Tapocik JD, Barbier E, Damadzic R, Eskay RL, Sun H, Rowe KE, King CE, Yao M, Flanigan ME, Solomon MG, Karlsson C, Cheng K, Rice KC, Heilig M. Schank JR, et al. Among authors: flanigan me. Biol Psychiatry. 2013 Apr 15;73(8):774-81. doi: 10.1016/j.biopsych.2012.12.027. Epub 2013 Feb 16. Biol Psychiatry. 2013. PMID: 23419547 Free PMC article.
A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in rats.
Thorsell A, Tapocik JD, Liu K, Zook M, Bell L, Flanigan M, Patnaik S, Marugan J, Damadzic R, Dehdashti SJ, Schwandt ML, Southall N, Austin CP, Eskay R, Ciccocioppo R, Zheng W, Heilig M. Thorsell A, et al. Among authors: flanigan m. J Neurosci. 2013 Jun 12;33(24):10132-42. doi: 10.1523/JNEUROSCI.4742-12.2013. J Neurosci. 2013. PMID: 23761908 Free PMC article.
178 results