Boehm MF - Search Results

1

Synthesis and characterization of heteroarotinoids demonstrate structure specificity relationships.

Benbrook DM, Subramanian S, Gale JB, Liu S, Brown CW, Boehm MF, Berlin KD. Benbrook DM, et al. Among authors: boehm mf. J Med Chem. 1998 Sep 10;41(19):3753-7. doi: 10.1021/jm980308p. J Med Chem. 1998. PMID: 9733501

2

Design, synthesis, and structure-activity relationship studies of novel 6,7-locked-[7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta]-2,4,6-trienoic acids.

Michellys PY, Ardecky RJ, Chen JH, D'Arrigo J, Grese TA, Karanewsky DS, Leibowitz MD, Liu S, Mais DA, Mapes CM, Montrose-Rafizadeh C, Ogilvie KM, Reifel-Miller A, Rungta D, Thompson AW, Tyhonas JS, Boehm MF. Michellys PY, et al. Among authors: boehm mf. J Med Chem. 2003 Sep 11;46(19):4087-103. doi: 10.1021/jm020401k. J Med Chem. 2003. PMID: 12954061

3

Novel (2E,4E,6Z)-7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta-2,4,6-trienoic acid retinoid X receptor modulators are active in models of type 2 diabetes.

Michellys PY, Ardecky RJ, Chen JH, Crombie DL, Etgen GJ, Faul MM, Faulkner AL, Grese TA, Heyman RA, Karanewsky DS, Klausing K, Leibowitz MD, Liu S, Mais DA, Mapes CM, Marschke KB, Reifel-Miller A, Ogilvie KM, Rungta D, Thompson AW, Tyhonas JS, Boehm MF. Michellys PY, et al. Among authors: boehm mf. J Med Chem. 2003 Jun 19;46(13):2683-96. doi: 10.1021/jm020340q. J Med Chem. 2003. PMID: 12801232

4

Design and synthesis of novel RXR-selective modulators with improved pharmacological profile.

Michellys PY, Boehm MF, Chen JH, Grese TA, Karanewsky DS, Leibowitz MD, Liu S, Mais DA, Mapes CM, Reifel-Miller A, Ogilvie KM, Rungta D, Thompson AW, Tyhonas JS, Yumibe N, Ardecky RJ. Michellys PY, et al. Among authors: boehm mf. Bioorg Med Chem Lett. 2003 Nov 17;13(22):4071-5. doi: 10.1016/j.bmcl.2003.08.048. Bioorg Med Chem Lett. 2003. PMID: 14592510

5

Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids.

Boehm MF, Zhang L, Badea BA, White SK, Mais DE, Berger E, Suto CM, Goldman ME, Heyman RA. Boehm MF, et al. J Med Chem. 1994 Sep 2;37(18):2930-41. doi: 10.1021/jm00044a014. J Med Chem. 1994. PMID: 8071941

6

Synthesis of high specific activity [3H]-9-cis-retinoic acid and its application for identifying retinoids with unusual binding properties.

Boehm MF, McClurg MR, Pathirana C, Mangelsdorf D, White SK, Hebert J, Winn D, Goldman ME, Heyman RA. Boehm MF, et al. J Med Chem. 1994 Feb 4;37(3):408-14. doi: 10.1021/jm00029a013. J Med Chem. 1994. PMID: 8308867

7

Discovery of novel retinoic acid receptor agonists having potent antiproliferative activity in cervical cancer cells.

Zhang L, Nadzan AM, Heyman RA, Love DL, Mais DE, Croston G, Lamph WW, Boehm MF. Zhang L, et al. Among authors: boehm mf. J Med Chem. 1996 Jul 5;39(14):2659-63. doi: 10.1021/jm960285j. J Med Chem. 1996. PMID: 8709094

8

Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells.

Boehm MF, Zhang L, Zhi L, McClurg MR, Berger E, Wagoner M, Mais DE, Suto CM, Davies JA, Heyman RA, et al. Boehm MF, et al. J Med Chem. 1995 Aug 4;38(16):3146-55. doi: 10.1021/jm00016a018. J Med Chem. 1995. PMID: 7636877

9

Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents.

Singh Ahuja H, Liu S, Crombie DL, Boehm M, Leibowitz MD, Heyman RA, Depre C, Nagy L, Tontonoz P, Davies PJ. Singh Ahuja H, et al. Mol Pharmacol. 2001 Apr;59(4):765-73. doi: 10.1124/mol.59.4.765. Mol Pharmacol. 2001. PMID: 11259621

10

Design, synthesis and structure-activity relationship of novel RXR-selective modulators.

Michellys PY, D'Arrigo J, Grese TA, Karanewsky DS, Leibowitz MD, Mais DA, Mapes CM, Reifel-Miller A, Rungta D, Boehm MF. Michellys PY, et al. Among authors: boehm mf. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1593-8. doi: 10.1016/j.bmcl.2003.12.089. Bioorg Med Chem Lett. 2004. PMID: 15006411

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