Froelich CJ - Search Results

1

Pro-caspase-3 is a major physiologic target of caspase-8.

Stennicke HR, Jürgensmeier JM, Shin H, Deveraux Q, Wolf BB, Yang X, Zhou Q, Ellerby HM, Ellerby LM, Bredesen D, Green DR, Reed JC, Froelich CJ, Salvesen GS. Stennicke HR, et al. Among authors: froelich cj. J Biol Chem. 1998 Oct 16;273(42):27084-90. doi: 10.1074/jbc.273.42.27084. J Biol Chem. 1998. PMID: 9765224 Free article.

2

Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.

Yang X, Stennicke HR, Wang B, Green DR, Jänicke RU, Srinivasan A, Seth P, Salvesen GS, Froelich CJ. Yang X, et al. Among authors: froelich cj. J Biol Chem. 1998 Dec 18;273(51):34278-83. doi: 10.1074/jbc.273.51.34278. J Biol Chem. 1998. PMID: 9852092 Free article.

3

Purification and use of granzyme B.

Shi L, Yang X, Froelich CJ, Greenberg AH. Shi L, et al. Among authors: froelich cj. Methods Enzymol. 2000;322:125-43. doi: 10.1016/s0076-6879(00)22013-2. Methods Enzymol. 2000. PMID: 10914010

4

Lymphocyte granule-mediated apoptosis: matters of viral mimicry and deadly proteases.

Froelich CJ, Dixit VM, Yang X. Froelich CJ, et al. Immunol Today. 1998 Jan;19(1):30-6. doi: 10.1016/s0167-5699(97)01184-5. Immunol Today. 1998. PMID: 9465486 Review. No abstract available.

5

Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis.

Yang XH, Sladek TL, Liu X, Butler BR, Froelich CJ, Thor AD. Yang XH, et al. Among authors: froelich cj. Cancer Res. 2001 Jan 1;61(1):348-54. Cancer Res. 2001. PMID: 11196185

6

Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment.

Froelich CJ, Hanna WL, Poirier GG, Duriez PJ, D'Amours D, Salvesen GS, Alnemri ES, Earnshaw WC, Shah GM. Froelich CJ, et al. Biochem Biophys Res Commun. 1996 Oct 23;227(3):658-65. doi: 10.1006/bbrc.1996.1565. Biochem Biophys Res Commun. 1996. PMID: 8885990

7

Granule-mediated killing: pathways for granzyme B-initiated apoptosis.

Talanian RV, Yang X, Turbov J, Seth P, Ghayur T, Casiano CA, Orth K, Froelich CJ. Talanian RV, et al. Among authors: froelich cj. J Exp Med. 1997 Oct 20;186(8):1323-31. doi: 10.1084/jem.186.8.1323. J Exp Med. 1997. PMID: 9334372 Free PMC article.

8

Granzyme B-induced and caspase 3-dependent cleavage of gelsolin by mouse cytotoxic T cells modifies cytoskeleton dynamics.

Martin P, Pardo J, Schill N, Jöckel L, Berg M, Froelich CJ, Wallich R, Simon MM. Martin P, et al. Among authors: froelich cj. J Biol Chem. 2010 Jun 11;285(24):18918-27. doi: 10.1074/jbc.M109.056028. Epub 2010 Apr 15. J Biol Chem. 2010. PMID: 20395300 Free PMC article.

9

New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis.

Froelich CJ, Orth K, Turbov J, Seth P, Gottlieb R, Babior B, Shah GM, Bleackley RC, Dixit VM, Hanna W. Froelich CJ, et al. J Biol Chem. 1996 Nov 15;271(46):29073-9. doi: 10.1074/jbc.271.46.29073. J Biol Chem. 1996. PMID: 8910561 Free article.

10

Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events.

Han J, Goldstein LA, Gastman BR, Froelich CJ, Yin XM, Rabinowich H. Han J, et al. Among authors: froelich cj. J Biol Chem. 2004 May 21;279(21):22020-9. doi: 10.1074/jbc.M313234200. Epub 2004 Mar 10. J Biol Chem. 2004. PMID: 15014070 Free article.

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